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Anti-Slc22A17 antibody produced in rabbit

Name: Anti-Slc22A17 antibody produced in rabbit
Brand: SIGMA
Price: 584 USD

affinity isolated antibody, buffered aqueous solution

Synonym(s):

Anti-BOCT, Anti-BOIT, Anti-Brain-type organic cation transporter, Anti-Solute carrier family 22 member 17

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Pack Size	SKU	Availability	Price
100 μg		Check Cart for Availability	$584.00

About This Item

NACRES:

NA.41

UNSPSC Code:

12352203

Conjugate:

unconjugated

Clone:

polyclonal

Application:

ELISA (i), IF, IHC, WB

Citations:

$584.00

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Properties

biological source

rabbit

Quality Level

100

conjugate

unconjugated

antibody form

affinity isolated antibody

antibody product type

primary antibodies

clone

polyclonal

form

buffered aqueous solution

mol wt

predicted mol wt 59 kDa

species reactivity

rat, human, mouse

technique(s)

immunohistochemistry: suitable, indirect ELISA: suitable, indirect immunofluorescence: suitable, western blot: suitable

NCBI accession no.

Q8WUG5

UniProt accession no.

Q8WUG5

shipped in

dry ice

storage temp.

−20°C

target post-translational modification

unmodified

Gene Information

human ... SLC22A17(51310)

Description

General description

Slc22A17 gene is also referred to as brain organic cation transporter (BOCT) and is mapped to human chromosome 14q11.2. The encoded protein is predominantly localized to kidney and liver. The Slc22 proteins consists of 12 transmembrane (TM) α-helices with an extended loop (extracellular) between the first and the second transmembrane regions, and a loop (intracellular) between the sixth and the seventh transmembrane regions.

Immunogen

Slc22A17 antibody was raised against a 14 amino acid peptide near the carboxy terminus of the human Slc22A17.

Biochem/physiol Actions

Slc22A17 expression is associated with important biological processes such as cell differentiation, apoptosis and inflammation. Slc22A17 mediates endocytosis of neutrophil gelatinase-associated lipocalin, a mammalian protein that can bind to bacterial siderophore enterobactin with high affinity.

Features and Benefits

Evaluate our antibodies with complete peace of mind. If the antibody does not perform in your application, we will issue a full credit or replacement antibody. Learn more.

Physical form

Supplied in PBS with 0.02% sodium azide.

Other Notes

The action of this antibody can be blocked using blocking peptide SBP3500306.

Disclaimer

Unless otherwise stated in our catalog or other company documentation accompanying the product(s), our products are intended for research use only and are not to be used for any other purpose, which includes but is not limited to, unauthorized commercial uses, in vitro diagnostic uses, ex vivo or in vivo therapeutic uses or any type of consumption or application to humans or animals.

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Show Differences

1 of 1

This Item	ABC846	HPA002728	SAB2102177
Sigma-Aldrich SAB3500306 Anti-Slc22A17 antibody produced in rabbit	Sigma-Aldrich ABC846 Anti-Slc22A17 Antibody	Sigma-Aldrich HPA002728 Anti-SLC22A17 antibody produced in rabbit	Sigma-Aldrich SAB2102177 Anti-SLC22A6 (ab2) antibody produced in rabbit
biological source rabbit	biological source rabbit	biological source rabbit	biological source rabbit
conjugate unconjugated	conjugate unconjugated	conjugate unconjugated	conjugate unconjugated
antibody form affinity isolated antibody	antibody form affinity isolated antibody	antibody form affinity isolated antibody	antibody form affinity isolated antibody
Quality Level 100	Quality Level 100	Quality Level 100	Quality Level 100
shipped in dry ice	shipped in wet ice	shipped in wet ice	shipped in wet ice
clone polyclonal	clone polyclonal	clone polyclonal	clone polyclonal

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Storage Class

10 - Combustible liquids

wgk

WGK 2

flash_point_f

Not applicable

flash_point_c

Not applicable

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Certificates of Analysis (COA)

Lot/Batch Number

465108031

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Articles

Protein-based Drug Transport

Protein-based drug transporters are expressed in Sf9 cells. Understanding the specific mechanisms of tumor cell transporters is an essential aspect of chemotherapeutic drug design.

Biochemical and structural characterization of the interaction between the Siderocalin NGAL/LCN2 and the N-terminal domain of its endocytic receptor SLC22A17.

Martinez A I C, et al.

The Journal of Biological Chemistry (2015)

Identification of six putative human transporters with structural similarity to the drug transporter SLC22 family.

Josefin A Jacobsson et al.

Genomics, 90(5), 595-609 (2007-08-24)

The solute carrier family 22 (SLC22) is a large family of organic cation and anion transporters. These are transmembrane proteins expressed predominantly in kidneys and liver and mediate the uptake and excretion of environmental toxins, endogenous substances, and drugs from

Global Trade Item Number

SKU	GTIN
SBP3500306-0.05MG	04061832169019
SAB3500306-100UG	04061832179452

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