Key Documents

View All Documentation

Anti-SKA2 antibody produced in rabbit

Name: Anti-SKA2 antibody produced in rabbit
Brand: SIGMA
Price: 723 CAD

affinity isolated antibody, buffered aqueous solution

Synonym(s):

Anti-FAM33A, Anti-Spindle and kinetochore associated complex subunit 2

Select a Size

Change View

Pack Size	SKU	Availability	Price
100 μg		Please contact Customer Service for Availability	$723.00

About This Item

NACRES:

NA.41

UNSPSC Code:

12352203

Conjugate:

unconjugated

Clone:

polyclonal

Application:

ELISA (i), WB

Citations:

$723.00

Please contact Customer Service for Availability

Technical Service

Need help? Our team of experienced scientists is here for you.

Let Us Assist

Properties

biological source

rabbit

Quality Segment

100

conjugate

unconjugated

antibody form

affinity isolated antibody

antibody product type

primary antibodies

clone

polyclonal

form

buffered aqueous solution

species reactivity

human, mouse

technique(s)

indirect ELISA: suitable, western blot: suitable

NCBI accession no.

NP_872426

UniProt accession no.

Q8WVK7

shipped in

dry ice

storage temp.

−20°C

target post-translational modification

unmodified

Gene Information

human ... SKA2(348235)

Description

General description

Upon entry into mitosis, the cell′s microtubule (MT) network forms the mitotic spindle, allowing the segregation of paired chromosomes. Proteinaceous structures on centromeric chromatin termed kinetochores (KT) are essential for the proper attachment of the chromosomes to the spindle MTs. A recently discovered spindle and kinetochore complex, comprised of proteins SKA1, SKA2, and SKA3, has been found to be required for stable KT-MT interactions and timely anaphase onset. Depletion of either SKA1 or SKA2 by siRNA results in the loss of both proteins from the KT, but does not impact overall KT structure. Cells depleted of the SKA complex undergo a prolonged checkpoint-dependent delay in a metaphase-like state, indicating the importance of the SKA complex in the maintenance of the metaphase plate and spindle checkpoint silencing. SKA2 has also been shown to interact with glucocorticoid receptors and to be involved in glucocorticoid signaling and cell proliferation.

Immunogen

SKA2 antibody was raised against a 15 amino acid peptide from near the amino terminus of human SKA2.

Features and Benefits

Evaluate our antibodies with complete peace of mind. If the antibody does not perform in your application, we will issue a full credit or replacement antibody. Learn more.

Physical form

Supplied at approx. 1 mg/mL in phosphate buffered saline containing 0.02% sodium azide.

Other Notes

The action of this antibody can be blocked using blocking peptide SBP3500102.

Disclaimer

Unless otherwise stated in our catalog or other company documentation accompanying the product(s), our products are intended for research use only and are not to be used for any other purpose, which includes but is not limited to, unauthorized commercial uses, in vitro diagnostic uses, ex vivo or in vivo therapeutic uses or any type of consumption or application to humans or animals.

Compare Similar Items

View Full Comparison

Show Differences

1 of 1

This Item	HPA059235	SAB5701496	HPA051196
Sigma-Aldrich SAB3500102 Anti-SKA2 antibody produced in rabbit	Sigma-Aldrich HPA059235 Anti-SKA2 antibody produced in rabbit	Sigma-Aldrich SAB5701496 Anti-SKP2 antibody produced in rabbit	Sigma-Aldrich HPA051196 Anti-SKP2 antibody produced in rabbit
biological source rabbit	biological source rabbit	biological source rabbit	biological source rabbit
Quality Level 100	Quality Level 100	Quality Level 100	Quality Level 100
antibody form affinity isolated antibody	antibody form affinity isolated antibody	antibody form -	antibody form affinity isolated antibody
conjugate unconjugated	conjugate unconjugated	conjugate unconjugated	conjugate unconjugated
technique(s) indirect ELISA: suitable, western blot: suitable	technique(s) immunohistochemistry: 1:50- 1:200	technique(s) immunohistochemistry: 1:50-1:200, western blot: 1:500-1:2000	technique(s) immunoblotting: 0.04-0.4 μg/mL, immunofluorescence: 0.25-2 μg/mL
clone polyclonal	clone polyclonal	clone monoclonal	clone polyclonal

Still not finding the right product?

Explore all of our products under Anti-SKA2 antibody produced in rabbit

— or —

Try our Product Selector Tool to narrow your options

Storage Class

10 - Combustible liquids

wgk

WGK 2

flash_point_f

Not applicable

flash_point_c

Not applicable

Choose from one of the most recent versions:

Certificates of Analysis (COA)

Lot/Batch Number

54030904

Don't see the Right Version?

If you require a particular version, you can look up a specific certificate by the Lot or Batch number.

Search for a COA

Already Own This Product?

Find documentation for the products that you have recently purchased in the Document Library.

Visit the Document Library

Global Trade Item Number

SKU	GTIN
SBP3500102-0.05MG	04061832167145
SAB3500102-100UG	04061832494432

Questions

Reviews

No rating value