Key Documents

Anti-ZBP1 antibody produced in rabbit

Name: Anti-ZBP1 antibody produced in rabbit
Brand: SIGMA
Price: 580 USD

affinity isolated antibody, buffered aqueous solution

Synonym(s):

ZBP1 Antibody - Anti-ZBP1 antibody produced in rabbit, Zbp1 Antibody, Anti-DAI, Anti-DLM-1, Anti-Z-DNA binding protein 1

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Pack Size	SKU	Availability	Price
100 μg		Check Cart for Availability	$580.00

About This Item

NACRES:

NA.41

UNSPSC Code:

12352203

Conjugate:

unconjugated

Clone:

polyclonal

Application:

ELISA (i), IF, IHC, WB

Citations:

$580.00

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Properties

biological source

rabbit

Quality Level

100

conjugate

unconjugated

antibody form

affinity isolated antibody

antibody product type

primary antibodies

clone

polyclonal

form

buffered aqueous solution

mol wt

predicted mol wt 39-45 kDa

species reactivity

human, rat, mouse

technique(s)

immunofluorescence: suitable, immunohistochemistry: suitable, indirect ELISA: suitable, western blot: suitable

UniProt accession no.

Q9H171

shipped in

dry ice

storage temp.

−20°C

target post-translational modification

unmodified

Gene Information

human ... ZBP1(81030)

Description

General description

Z-DNA binding protein 1 (ZBP1), also known as interferon (IFN) γ-inducible gene, is a cytoplasmic DNA sensor. It belongs to the family of Z-DNA binding proteins. ZBP1 is majorly expressed in the small intestine and lymphatic tissues. The gene is located on human chromosome 20q13.3.

Immunogen

a 18 amino acid peptide from near the carboxy-terminus of human ZBP1.

Application

Anti-ZBP1 antibody produced in rabbit has been used for western blotting.

Biochem/physiol Actions

Z-DNA binding protein 1 (ZBP1) plays a major role in DNA mediated innate immune responses. It enhances nuclear factor k-light-chain-enhancer of activated B cells (NFκB) activation and proinflammatory cytokine production.

Physical form

Solution in phosphate buffered saline containing 0.02% sodium azide

Other Notes

The action of this antibody can be blocked using blocking peptide SBP4401.

Disclaimer

Unless otherwise stated in our catalog or other company documentation accompanying the product(s), our products are intended for research use only and are not to be used for any other purpose, which includes but is not limited to, unauthorized commercial uses, in vitro diagnostic uses, ex vivo or in vivo therapeutic uses or any type of consumption or application to humans or animals.

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This Item	HPA041256	SAB4500913	AV42081
Sigma-Aldrich PRS4401 Anti-ZBP1 antibody produced in rabbit	Sigma-Aldrich HPA041256 Anti-ZBP1 antibody produced in rabbit	Sigma-Aldrich SAB4500913 Anti-ZP1 antibody produced in rabbit	$Anti-RBP1 antibody produced in rabbit IgG fraction of antiserum$ Sigma-Aldrich AV42081 Anti-RBP1 antibody produced in rabbit
biological source rabbit	biological source rabbit	biological source rabbit	biological source rabbit
conjugate unconjugated	conjugate unconjugated	conjugate unconjugated	conjugate unconjugated
Quality Level 100	Quality Level 100	Quality Level -	Quality Level -
antibody form affinity isolated antibody	antibody form affinity isolated antibody	antibody form affinity isolated antibody	antibody form IgG fraction of antiserum
Gene Information human ... ZBP1(81030)	Gene Information human ... ZBP1(81030)	Gene Information human ... ZP1(22917)	Gene Information human ... RBP1(5947)
technique(s) immunofluorescence: suitable, indirect ELISA: suitable, immunohistochemistry: suitable, western blot: suitable	technique(s) immunohistochemistry: 1:1000- 1:2500	technique(s) ELISA: 1:10000, western blot: 1:500-1:1000	technique(s) western blot: suitable

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Storage Class

10 - Combustible liquids

wgk

WGK 2

flash_point_f

Not applicable

flash_point_c

Not applicable

Choose from one of the most recent versions:

Certificates of Analysis (COA)

Lot/Batch Number

44011002

44010801

4401-0801

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ZBP1: innate sensor regulating cell death and inflammation

Kuriakose T and Kanneganti TD

Trends in Immunology, 39(2), 123-134 (2018)

Molecular Lesions of Insulator CTCF and Its Paralogue CTCFL (BORIS) in Cancer: An Analysis from Published Genomic Studies

Voutsadakis I

High Throughput, 7(4), 30-30 (2018)

Functional roles of pattern recognition receptors that recognize virus nucleic acids in human adipose-derived mesenchymal stem cells

Yu L, et al.

BioMed Research International, 2016 (2016)

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Global Trade Item Number

SKU	GTIN
SBP4401-0.05MG	04061832163611
PRS4401-100UG	04061832179117

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