Key Documents

Anti-OASL antibody produced in rabbit

Name: Anti-OASL antibody produced in rabbit
Brand: SIGMA
Price: 802 CAD

affinity isolated antibody, buffered aqueous glycerol solution

Synonym(s):

Anti-59 kDa 2′→5′-Oligoadenylate synthetase-like protein antibody produced in rabbit, Anti-TRIP-14 antibody produced in rabbit, Anti-Thyroid receptor-interacting protein 14 antibody produced in rabbit, Anti-p59 OASL antibody produced in rabbit, Anti-p59OASL antibody produced in rabbit

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Pack Size	SKU	Availability	Price
100 μL		Please contact Customer Service for Availability	$802.00

About This Item

UNSPSC Code:

12352203

NACRES:

NA.41

Human Protein Atlas Number:

HPA001474

Conjugate:

unconjugated

Clone:

polyclonal

Application:

Citations:

$802.00

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Properties

biological source

rabbit

Quality Segment

100

conjugate

unconjugated

antibody form

affinity isolated antibody

antibody product type

primary antibodies

clone

polyclonal

form

buffered aqueous glycerol solution

species reactivity

human

technique(s)

immunoblotting: 0.04-0.4 μg/mL, immunofluorescence: 0.25-2 μg/mL

immunogen sequence

EVLDAVRTVEEFLRQEHFQGKRGLDQDVRVLKVVKVGSFGNGTVLRSTREVELVAFLSCFHSFQEAAKHHKDVLRLIWKTMWQSQDLLDLGLEDLRMEQRVPDALVFTIQTRGTAEPITVTIVPAYRAL

UniProt accession no.

Q15646

shipped in

wet ice

storage temp.

−20°C

target post-translational modification

unmodified

Gene Information

human ... OASL(8638)

Description

Immunogen

59 kDa 2′→5′-Oligoadenylate synthetase-like protein recombinant protein epitope signature tag (PrEST)

Application

Anti-OASL antibody produced in rabbit, a Prestige Antibody, is developed and validated by the Human Protein Atlas (HPA) project . Each antibody is tested by immunohistochemistry against hundreds of normal and disease tissues. These images can be viewed on the Human Protein Atlas (HPA) site by clicking on the Image Gallery link. The antibodies are also tested using immunofluorescence and western blotting. To view these protocols and other useful information about Prestige Antibodies and the HPA, visit sigma.com/prestige.

Biochem/physiol Actions

OASL (2′-5′-oligoadenylate synthetase-like) is a 59kDa protein that is an atypical member of the OAS family as it does not possess the characteristic 2′-5′ oligoadenylate synthetase activity. It exhibits an antiviral effect against the single-stranded RNA viruses, such as, picornavirus, encephalomyocarditis virus. It inhibits hepatitis C viral replication in vitro. OASL interacts with the transcriptional repressor Methyl CpG-binding protein 1 (MBD1) upon interferon stimulation.

Features and Benefits

Prestige Antibodies^® are highly characterized and extensively validated antibodies with the added benefit of all available characterization data for each target being accessible via the Human Protein Atlas portal linked just below the product name at the top of this page. The uniqueness and low cross-reactivity of the Prestige Antibodies^® to other proteins are due to a thorough selection of antigen regions, affinity purification, and stringent selection. Prestige antigen controls are available for every corresponding Prestige Antibody and can be found in the linkage section.

Every Prestige Antibody is tested in the following ways:

IHC tissue array of 44 normal human tissues and 20 of the most common cancer type tissues.
Protein array of 364 human recombinant protein fragments.

Physical form

Solution in phosphate-buffered saline, pH 7.2, containing 40% glycerol and 0.02% sodium azide

Other Notes

Corresponding Antigen APREST83083

Legal Information

Prestige Antibodies is a registered trademark of Merck KGaA, Darmstadt, Germany

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This Item	HPA000525	HPA006889	HPA000449
Sigma-Aldrich HPA001474 Anti-OASL antibody produced in rabbit	Sigma-Aldrich HPA000525 Anti-ADSL antibody produced in rabbit	Sigma-Aldrich HPA006889 Anti-SORT1 antibody produced in rabbit	Sigma-Aldrich HPA000449 Anti-ESR1 antibody produced in rabbit
conjugate unconjugated	conjugate unconjugated	conjugate unconjugated	conjugate unconjugated
biological source rabbit	biological source rabbit	biological source rabbit	biological source rabbit
Quality Level 100	Quality Level 100	Quality Level 100	Quality Level 100
antibody form affinity isolated antibody	antibody form affinity isolated antibody	antibody form affinity isolated antibody	antibody form affinity isolated antibody
species reactivity human	species reactivity human	species reactivity human	species reactivity human
Gene Information human ... OASL(8638)	Gene Information human ... ADSL(158)	Gene Information human ... SORT1(6272)	Gene Information human ... ESR1(2099)

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Storage Class

10 - Combustible liquids

wgk

WGK 1

ppe

Eyeshields, Gloves, multi-purpose combination respirator cartridge (US)

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Certificates of Analysis (COA)

Lot/Batch Number

R00644

R000644

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Global Trade Item Number

SKU	GTIN
HPA001474-100UL	04061835679058
HPA001474-25UL	04061842773008

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