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H8000

L-Histidine

≥99% (TLC), ReagentPlus®

Synonym(s):

(S)-2-Amino-3-(4-imidazolyl)propionic acid, NSC 137773

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Pack SizeSKUAvailabilityPrice
5 g
Please contact Customer Service for Availability
$27.50
10 g

Available to ship TODAYfromMilliporeSigma Canada Ltd.

$39.40
25 g

Available to ship TODAYfromMilliporeSigma Canada Ltd.

$58.70
100 g

Available to ship TODAYfromMilliporeSigma Canada Ltd.

$201.00
500 g
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$782.00
1 kg
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$1,180.00
5 kg

Available to ship TODAYfromMilliporeSigma Canada Ltd.

$4,930.00

About This Item

Empirical Formula (Hill Notation):
C6H9N3O2
CAS Number:
Molecular Weight:
155.15
PubChem Substance ID:
eCl@ss:
32160406
UNSPSC Code:
12352209
NACRES:
NA.26
EC Number:
200-745-3
MDL number:
Beilstein/REAXYS Number:
84088

$27.50


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Product Name

L-Histidine, ReagentPlus®, ≥99% (TLC)

Quality Level

product line

ReagentPlus®

assay

≥99% (TLC)

form

powder

color

white to off-white

mp

282 °C (dec.) (lit.)

solubility

0.5 M HCl: 50 mg/mL

application(s)

cell analysis

SMILES string

N[C@@H](Cc1c[nH]cn1)C(O)=O

InChI

1S/C6H9N3O2/c7-5(6(10)11)1-4-2-8-3-9-4/h2-3,5H,1,7H2,(H,8,9)(H,10,11)/t5-/m0/s1

InChI key

HNDVDQJCIGZPNO-YFKPBYRVSA-N

Gene Information

human ... CA1(759), CA2(760)

Application

L-histidine has been used for the selection of transformed cells. It has also been used to study its effects on the formation of verteporfin cross-linked oligomers in cellular homogenates.

Biochem/physiol Actions

Precursor of histamine by action of histidine decarboxylase.
L-Histidine is an essential amino acid. It binds to metal ions and may aid in the transport of copper. Histidine is widely present at the active sites of enzymes. It also has a role in binding of heme groups, macromolecules and phosphate groups in the binding sites of proteins.

Legal Information

ReagentPlus is a registered trademark of Merck KGaA, Darmstadt, Germany

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1 of 1

This Item
53319H391173767
form

powder

form

powder or crystals

form

crystalline powder

form

-

assay

≥99% (TLC)

assay

≥99.5% (NT)

assay

≥98.5%

assay

-

product line

ReagentPlus®

product line

BioUltra

product line

-

product line

TraceCERT®

Quality Level

200

Quality Level

200

Quality Level

400

Quality Level

300

color

white to off-white

color

white

color

-

color

-

solubility

0.5 M HCl: 50 mg/mL

solubility

H2O: 0.1 M at 20 °C, clear, colorless

solubility

H2O: 50 mg/mL

solubility

-


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Storage Class

11 - Combustible Solids

wgk

WGK 1

flash_point_f

Not applicable

flash_point_c

Not applicable

ppe

Eyeshields, Gloves, type N95 (US)



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Articles

Amino Acid Codon Wheel for fast RNA translation. Find which amino acid is translated from your RNA sequence quickly and easily.


Verteporfin-induced formation of protein cross-linked oligomers and high molecular weight complexes is mediated by light and leads to cell toxicity
Eleni K
Scientific Reports (2017)
Roger L. Lundblad
Chemical Reagents for Protein Modification (2014)
Catherine Collin, Masaru Minami, Hasan Parvez, Hideya Saito, Simone Parvez, Qureshi, Claude Reiss
Advances in Neurochemistry (2005)



Global Trade Item Number

SKUGTIN
H8000-25G04061835361342
H8000-5G04061835361366
H8000-10G04061835361335
H8000-5KG04061833804957
H8000-500G04061835361359
H8000-100G04061835361328
H8000-1KG04061833804933

Questions

1–3 of 3 Questions  
  1. How can I determine the shelf life / expiration / retest date of this product?

    1 answer
    1. If this product has an expiration or retest date, it will be shown on the Certificate of Analysis (COA, CofA). If there is no retest or expiration date listed on the product's COA, we do not have suitable stability data to determine a shelf life. For these products, the only date on the COA will be the release date; a retest, expiration, or use-by-date will not be displayed.
      For all products, we recommend handling per defined conditions as printed in our product literature and website product descriptions. We recommend that products should be routinely inspected by customers to ensure they perform as expected.
      For products without retest or expiration dates, our standard warranty of 1 year from the date of shipment is applicable.
      For more information, please refer to the Product Dating Information document: https://www.sigmaaldrich.com/deepweb/assets/sigmaaldrich/marketing/global/documents/418/501/product-dating-information-06-25-mk.pdf

      Helpful?

  2. How is shipping temperature determined? And how is it related to the product storage temperature?

    1 answer
    1. Products may be shipped at a different temperature than the recommended long-term storage temperature. If the product quality is sensitive to short-term exposure to conditions other than the recommended long-term storage, it will be shipped on wet or dry-ice. If the product quality is NOT affected by short-term exposure to conditions other than the recommended long-term storage, it will be shipped at ambient temperature. As shipping routes are configured for minimum transit times, shipping at ambient temperature helps control shipping costs for our customers. For more information, please refer to the Storage and Transport Conditions document: https://www.sigmaaldrich.com/deepweb/assets/sigmaaldrich/marketing/global/documents/316/622/storage-transport-conditions-mk.pdf

      Helpful?

  3. What is the solubility of L-Histidine (H8000) in water?

    1 answer
    1. L-Histidine is fairly soluble in water but insoluble in alcohol and ether. It decomposes at a temperature of 251-252 °C. When dissolved in water, a clear solution can be achieved at a concentration of 50 mg/ml with 0.5 M hydrochloric acid.

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