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900533

(t-Bu)PhCPhos Pd G4

95%, powder or crystals

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Pack SizeSKUAvailabilityPrice
250 mg
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$265.00

About This Item

Empirical Formula (Hill Notation):
C40H48N3O3PPdS
CAS Number:
Molecular Weight:
788.29
UNSPSC Code:
12161600
NACRES:
NA.22

$265.00


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Product Name

(t-Bu)PhCPhos Pd G4, 95%

Quality Level

product line

Buchwald precatalyst Generation 4

assay

95%

form

powder or crystals

feature

generation 4

reaction suitability

core: palladium, reaction type: Buchwald-Hartwig Cross Coupling Reaction, reaction type: Heck Reaction, reaction type: Hiyama Coupling, reaction type: Negishi Coupling, reaction type: Sonogashira Coupling, reaction type: Stille Coupling, reaction type: Suzuki-Miyaura Coupling, reagent type: catalyst
reaction type: Cross Couplings

functional group

phosphine

SMILES string

O=S(=O)([O-][Pd+2]1([C-]=2C=CC=CC2C=3C=CC=CC3[NH]1C)[P](C=4C=CC=CC4)(C5=CC=CC=C5C=6C(=CC=CC6N(C)C)N(C)C)C(C)(C)C)C

InChI

InChI=1S/C26H33N2P.C13H12N.CH4O3S.Pd/c1-26(2,3)29(20-14-9-8-10-15-20)24-19-12-11-16-21(24)25-22(27(4)5)17-13-18-23(25)28(6)7;1-14-13-10-6-5-9-12(13)11-7-3-2-4-8-11;1-5(2,3)4;/h8-19H,1-7H3;2-7,9-10,14H,1H3;1H3,(H,2,3,4);/q;-1;;+2/p-1

Application

A fourth generation (G4) Buchwald precatalyst that is similar to the third generation (G3) precatalysts except that the amino group on the biphenyl backbone is methylated. This modification helps to prevent the limitations found when using the third generation precatalysts. It is air, moisture, and thermally-stable and shows good solubility in common organic solvents.

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This Item
900534901220900471
reaction suitability

core: palladium, reaction type: Heck Reaction, reaction type: Negishi Coupling, reaction type: Stille Coupling, reagent type: catalyst
reaction type: Cross Couplings, reaction type: Buchwald-Hartwig Cross Coupling Reaction, reaction type: Sonogashira Coupling, reaction type: Hiyama Coupling, reaction type: Suzuki-Miyaura Coupling

reaction suitability

-

reaction suitability

-

reaction suitability

core: palladium, reaction type: Buchwald-Hartwig Cross Coupling Reaction, reaction type: Heck Reaction, reaction type: Hiyama Coupling, reaction type: Negishi Coupling, reaction type: Sonogashira Coupling, reaction type: Stille Coupling, reaction type: Suzuki-Miyaura Coupling, reagent type: catalyst
reaction type: Cross Couplings

assay

95%

assay

≥95%

assay

-

assay

95%

form

powder or crystals

form

powder

form

powder or crystals

form

powder or crystals

Quality Level

100

Quality Level

100

Quality Level

100

Quality Level

100

feature

generation 4

feature

generation 3

feature

generation 4

feature

generation 4

product line

Buchwald precatalyst Generation 4

product line

Buchwald precatalyst Generation 3

product line

Buchwald precatalyst Generation 4

product line

Buchwald precatalyst Generation 4


Storage Class

11 - Combustible Solids

wgk

WGK 3

flash_point_f

Not applicable

flash_point_c

Not applicable



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Articles

G3 and G4 Buchwald palladium precatalysts are the newest air, moisture, and thermally stable crossing-coupling complexes used in bond formation for their versatility and high reactivity.


Nathaniel H Park et al.
Angewandte Chemie (International ed. in English), 54(28), 8259-8262 (2015-06-03)
In Pd-catalyzed C-N cross-coupling reactions, α-branched secondary amines are difficult coupling partners and the desired products are often produced in low yields. In order to provide a robust method for accessing N-aryl α-branched tertiary amines, new catalysts have been designed



Global Trade Item Number

SKUGTIN
900533-250MG04061833250259

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