跳轉至內容
Merck
  • Compounded preparations with nystatin for oral and oromucosal administration.

Compounded preparations with nystatin for oral and oromucosal administration.

Acta poloniae pharmaceutica (2013-08-08)
Zbynek Sklenár, Vladimír Scigel, Katerina Horácková, Ondrej Slanar
摘要

Therapy of oral, esophageal and gastrointestinal candidiasis is still a common problem that can be solved by an administration of antimycotics. Major disadvantage of registered commercial antifungal medicinal products is their price, so the health care system and its payers may profit from extemporaneous compounding. An appropriate drug therapy for candidiasis (trush) is nystatin, which is a substance available in the Czech Republic for the magistral preparation relatively recently, since 2010. Making formulas for extemporaneous compounding is quite simple and preparations particularly useful for dentists, pediatricians, otolaryngologists, oncologists and gastroenterologists. The authors formulated composition of viscous oromucosal suspension, oral/oromucosal hydrogel and oromucosal gelatine globule which may be present as compounded products containing nystatin for oromucosal and/or oral administration. The preparation is practically verified and magistral products have been already used in clinical practice.

材料
產品編號
品牌
產品描述

Sigma-Aldrich
甘油, ACS reagent, ≥99.5%
Sigma-Aldrich
甘油, for molecular biology, ≥99.0%
Sigma-Aldrich
甘油, ReagentPlus®, ≥99.0% (GC)
Sigma-Aldrich
明胶 溶液, Type B, 2% in H2O, tissue culture grade, BioReagent, suitable for cell culture
Sigma-Aldrich
明胶 来源于猪皮肤, gel strength 300, Type A
Sigma-Aldrich
明胶 来源于猪皮肤, powder, gel strength ~300 g Bloom, Type A, BioReagent, suitable for electrophoresis, suitable for cell culture
Sigma-Aldrich
甲基纤维素, viscosity: 4,000 cP
Sigma-Aldrich
明胶 来源于冷水鱼类的皮肤, solid
Sigma-Aldrich
明胶 来源于牛皮, Type B, powder, BioReagent, suitable for cell culture
Sigma-Aldrich
甘油 溶液, 83.5-89.5% (T)
Sigma-Aldrich
甘油, BioReagent, suitable for cell culture, suitable for insect cell culture, suitable for electrophoresis, ≥99% (GC)
Sigma-Aldrich
制霉菌素悬浮液, suspension, 10,000 unit/mL in DPBS, BioReagent, suitable for cell culture
Sigma-Aldrich
甘油, BioUltra, for molecular biology, anhydrous, ≥99.5% (GC)
Sigma-Aldrich
甘油, puriss., anhydrous, 99.0-101.0% (alkalimetric)
Sigma-Aldrich
木糖醇, ≥99% (GC)
Sigma-Aldrich
羟丙基 甲基纤维素, viscosity 2,600-5,600 cP, 2 % in H2O(20 °C)(lit.)
Sigma-Aldrich
甲基纤维素, viscosity: 15 cP, BioReagent, suitable for cell culture
Sigma-Aldrich
明胶 来源于牛皮, gel strength ~225 g Bloom, Type B
Sigma-Aldrich
甘油, FCC, FG
Sigma-Aldrich
甘油, puriss. p.a., ACS reagent, anhydrous, dist., ≥99.5% (GC)
Millipore
明胶 来源于猪皮肤, medium gel strength, suitable for microbiology
Sigma-Aldrich
明胶 来源于猪皮肤, gel strength ~175 g Bloom, Type A
Sigma-Aldrich
明胶 来源于猪皮肤, gel strength 80-120 g Bloom, Type A
Sigma-Aldrich
甲基纤维素, viscosity: 1,500 cP
Sigma-Aldrich
制霉菌素即用型溶液, powder, BioReagent, suitable for cell culture
Sigma-Aldrich
羟丙基 甲基纤维素
Sigma-Aldrich
明胶 来源于牛皮, Type B
Sigma-Aldrich
羟丙基 甲基纤维素, average Mn ~10,000
Sigma-Aldrich
甲基纤维素, viscosity: 15 cP
Sigma-Aldrich
羟丙基 甲基纤维素, viscosity 80-120 cP, 2 % in H2O(20 °C)(lit.)