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BP1100

硫酸羟氯喹

British Pharmacopoeia (BP) Reference Standard

同義詞:

7-氯-4-[4-(N-乙基-N-b-羟乙基氨基)-1-甲基丁氨基] 喹啉硫酸盐

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About This Item

經驗公式(希爾表示法):
C18H26ClN3O · H2SO4
CAS號碼:
分子量::
433.95
MDL號碼:
分類程式碼代碼:
41116107
NACRES:
NA.24

等級

pharmaceutical primary standard

agency

BP

API 家族

hydroxychloroquine

形狀

solid

儲存期限

limited shelf life, expiry date on the label

包裝

pkg of 100 mg

製造商/商標名

BP

顏色

off-white

mp

238-241 °C

溶解度

water: soluble

應用

pharmaceutical
pharmaceutical small molecule

格式

neat

運輸包裝

ambient

儲存溫度

2-8°C

SMILES 字串

OS(O)(=O)=O.CCN(CCO)CCCC(C)Nc1ccnc2cc(Cl)ccc12

InChI

1S/C18H26ClN3O.H2O4S/c1-3-22(11-12-23)10-4-5-14(2)21-17-8-9-20-18-13-15(19)6-7-16(17)18;1-5(2,3)4/h6-9,13-14,23H,3-5,10-12H2,1-2H3,(H,20,21);(H2,1,2,3,4)

InChI 密鑰

JCBIVZZPXRZKTI-UHFFFAOYSA-N

基因資訊

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一般說明

Hydroxychloroquine Sulfate (Hydroxychloroquine Sulphate) is a salt of hydroxychloroquine (HCQ, Plaquenil), a 4-aminoquinoline based antiviral drug.
This product is provided as delivered and specified by the issuing Pharmacopoeia. All information provided in support of this product, including SDS and any product information leaflets have been developed and issued under the Authority of the issuing Pharmacopoeia. For further information and support please go to the website of the issuing Pharmacopoeia.

應用

Hydroxychloroquine sulfate BP Reference standard, intended for use in laboratory tests only as specifically prescribed in the British Pharmacopoeia.

Also used in monographs such as:
  • Hydroxychloroquine Tablets
  • 生化/生理作用

    硫酸羟氯喹是一种抗炎(通过肿瘤坏死因子)、疾病调节抗风湿药物(DMARD)和血红素聚合酶抑制剂。 它可用于治疗疟疾。

    包裝

    Unit quantity: 100 mg. Subject to change. The product is delivered as supplied by the issuing Pharmacopoeia. For the current unit quantity please visit British Pharmacopoeia

    其他說明

    Sales restrictions may apply.

    象形圖

    Exclamation mark

    訊號詞

    Warning

    危險聲明

    危險分類

    Acute Tox. 4 Oral - Eye Irrit. 2 - Skin Irrit. 2

    儲存類別代碼

    11 - Combustible Solids

    水污染物質分類(WGK)

    WGK 3

    閃點(°F)

    Not applicable

    閃點(°C)

    Not applicable


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    分析證明 (COA)

    Lot/Batch Number

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    存取文件庫

    Famotidine
    British Pharmacopeia
    British Pharmacopoeia, 44(12), 1000-1004 (2020)
    Seminars in Arthritis and Rheumatism, 43(2), 264-272 (2013)
    A rapid and reliable method for the quantitation of hydroxychloroquine in serum using turbulent flow liquid chromatography-tandem mass spectrometry
    Fuzery AK, et al.
    Clinica Chimica Acta; International Journal of Clinical Chemistry, 421 (2013)
    Development of a novel ion-pairing HPLC-FL method for the separation and quantification of hydroxychloroquine and its metabolites in whole blood
    Charlier B,et al.
    Biomedical Chromatography, 32(8), e4258-e4258 (2018)
    Compatibility study of hydroxychloroquine sulfate with pharmaceutical excipients using thermal and nonthermal techniques for the development of hard capsules
    Moraes ANF, et al.
    Journal of Thermal Analysis and Calorimetry, 421 (2019)

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