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U4125

Sigma-Aldrich

尿苷 5′-（二磷酸三氢） 钠盐 来源于酿酒酵母

95-100%

同義詞:

UDP 钠盐, Uridine 5′-(trihydrogen pyrophosphate) 钠盐

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About This Item

經驗公式（希爾表示法）:
C9H14N2O12P2 · xNa+
CAS號碼:
21931-53-3
分子量：:
404.16 (free acid basis)
分類程式碼代碼:
12352200
PubChem物質ID:
24278767
NACRES:
NA.77
暫時無法取得訂價和供貨情況

化驗

95-100%

溶解度

H2O: soluble 100 mg/mL, clear, colorless to very faintly yellow

儲存溫度

−20°C

SMILES 字串

[Na+].[Na+].[Na+].O[C@H]1[C@@H](O)[C@@H](O[C@@H]1COP([O-])(=O)OP([O-])([O-])=O)N2C=CC(=O)NC2=O

InChI

1S/C9H14N2O12P2.3Na/c12-5-1-2-11(9(15)10-5)8-7(14)6(13)4(22-8)3-21-25(19,20)23-24(16,17)18;;;/h1-2,4,6-8,13-14H,3H2,(H,19,20)(H,10,12,15)(H2,16,17,18);;;/q;3*+1/p-3

InChI 密鑰

GFASEGWJDXDCKZ-UHFFFAOYSA-K

基因資訊

human ... LPAR4(2846) , LTB4R(1241) , P2RY1(5028) , P2RY10(27334) , P2RY11(5032) , P2RY12(64805) , P2RY13(53829) , P2RY14(9934) , P2RY2(5029) , P2RY4(5030) , P2RY5(10161) , P2RY6(5031) , P2RY8(286530)

相關類別

應用

UDP已用作嘌呤能激动剂，研究其对耳蜗外沟细胞（OSC）和前庭移行细胞（VTC）吸收阳离子通量的影响 [1]。UDP 还用于兔视网膜中核苷二磷酸酶（NDPase）活性测定 [2]。

生化／生理作用

P2Y 受体激动剂。

特點和優勢

该化合物的相关信息整理于受体分类和信号转导手册的 P2受体：P2Y G蛋白家族 页面。想要浏览手册的其他页面， 请单击此处。

準備報告

尿苷 5′-（三磷酸二氢钠）钠或 UDP 钠盐溶于水，浓度为 100 mg/mL，成为澄清、无色至微淡黄色溶液。

象形圖

Health hazard
GHS08

訊號詞

Warning

危險聲明

H371

危險分類

STOT SE 2

標靶器官

Eyes,Central nervous system

儲存類別代碼

11 - Combustible Solids

水污染物質分類（WGK）

WGK 3

閃點（°F）

Not applicable

閃點（°C）

Not applicable

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分析證明 (COA)

Lot/Batch Number
0000432619
0000432619
0000414881
0000414881
0000294607

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J H Lee et al.
The Journal of neuroscience : the official journal of the Society for Neuroscience, 21(23), 9168-9174 (2001-11-22)
Cochlear outer sulcus cells (OSC) and vestibular transitional cells (VTC) are part of the parasensory epithelium in the inner ear and are located in homologous positions between the sensory hair cells and the cation secretory epithelial cells in the cochlea
J Schnitzer
The Journal of comparative neurology, 282(2), 249-263 (1989-04-08)
Enzyme-histochemical methods for thiamine pyrophosphatase (TPPase) and nucleoside diphosphatase (NDPase) were applied to wholemounted rabbit retinae to demonstrate the shape and distribution of microglial cells in early postnatal and adult animals. At birth, microglial cells were already present in the
Markie O Muoboghare et al.
British journal of pharmacology, 176(16), 2894-2904 (2019-05-23)
There is a lack of potent, selective antagonists at most subtypes of P2Y receptor. The aims of this study were to characterise the pharmacological properties of the proposed P2Y2 receptor antagonist, AR-C118925XX, and then to use it to determine the
Hui Hong et al.
Cell chemical biology, 26(4), 493-501 (2019-02-05)
Malayamycin A is an unusual bicyclic C-nucleoside, with interesting antiviral, antifungal, and anticancer bioactivity. We report here the discovery and characterization of the biosynthetic pathway to malayamycin by using genome mining of near-identical clusters both from the known producer Streptomyces
Dhébora Albuquerque Dias et al.
Cell biochemistry and function, 35(7), 358-363 (2017-09-06)
This study aimed to characterize the activity of ectonucleoside triphosphate diphosphohydrolase (E-NTPDase; EC 3.6.1.5) in peritoneal cavity cells from BALB/c mice. E-NTPDase was activated in the presence of both calcium (1.5mM) and magnesium (1.5mM) ions. However, the activity was higher
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