The use of T1875 for in vivo application was discussed and cited in the following article as a protocol reference: J Neuroendocrinol. 2015 Feb; 27(2): 100–110. The article is titled "Prenatal Testosterone Excess Decreases Neurokinin 3 Receptor Immunoreactivity within the Arcuate Nucleus KNDy cell population" with the PMID: 25496429.
推薦產品
生物源
synthetic (organic)
品質等級
無菌
non-sterile
化驗
≥98% (HPLC)
形狀
solid
藥物控制
USDEA Schedule III; Home Office Schedule 4.2; regulated under CDSA - not available from Sigma-Aldrich Canada
顏色
white
溶解度
acetone: soluble 1 in 4 of acetone
chloroform: soluble 50 mg/ml, clear, colorless to faintly yellow
ethanol: soluble 1 in 6 of ethanol
ethyl oleate: soluble 1 in 20 of ethyl oleate
propylene glycol: soluble 1 in 30 of propylene glycol
soluble 1 in 20 of ethyl oleate
ethanol: 10 mg/mL
45% (w/v) aq 2-hydroxypropyl-β-cyclodextrin: 4.4 mg/mL
H2O: insoluble
oil: soluble
運輸包裝
ambient
儲存溫度
room temp
SMILES 字串
[H][C@@]12CCC3=CC(=O)CC[C@]3(C)[C@@]1([H])CC[C@]4(C)[C@H](CC[C@@]24[H])OC(=O)CC
InChI
1S/C22H32O3/c1-4-20(24)25-19-8-7-17-16-6-5-14-13-15(23)9-11-21(14,2)18(16)10-12-22(17,19)3/h13,16-19H,4-12H2,1-3H3/t16-,17-,18-,19-,21-,22-/m0/s1
InChI 密鑰
PDMMFKSKQVNJMI-BLQWBTBKSA-N
基因資訊
human ... AR(367) , CYP17A1(1586)
rat ... Ar(24208)
尋找類似的產品？ 前往 產品比較指南
生化／生理作用
Androgens direct the development of the male phenotype during embryogenesis and at puberty. Testosterone is an androgen that is secreted by the testis. This hormone is converted to dihydrotestosterone in the target tissues where it regulates several biological functions. Testosterone propionate has been synthetically derived from a plant. This product has extended and faster-acting functions when compared to other testosterone esters.
外觀
Photosensitive solid
準備報告
This product is soluble in chloroform (50 mg/ml). It is also soluble in various oils. The oil solutions can be sterilized by maintaining at 150 deg C for 1 hour. It is practically insoluble in water, soluble 1 in 6 of ethanol, 1 in 4 of acetone, 1 in 20 of ethyl oleate, and 1 in 30 of propylene glycol. The product is incompatible with alkalis and oxidizing agents and it should be protected from light.
訊號詞
Danger
危險分類
Acute Tox. 4 Oral - Aquatic Acute 1 - Carc. 2 - Repr. 1A
儲存類別代碼
6.1C - Combustible acute toxic Cat.3 / toxic compounds or compounds which causing chronic effects
水污染物質分類（WGK）
WGK 3
個人防護裝備
Eyeshields, Gloves, type P3 (EN 143) respirator cartridges
從最近期的版本中選擇一個：
分析證明 (COA)
Lot/Batch Number
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Endocrinology, 156(9), 3277-3291 (2015-06-11)
Prenatal testosterone (T)-treated ewes display a constellation of reproductive defects that closely mirror those seen in PCOS women, including altered hormonal feedback control of GnRH. Kisspeptin/neurokinin B/dynorphin (KNDy) neurons of the arcuate nucleus (ARC) play a key role in steroid
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