SRP3325

Uterglobin Peptide

≥98% (HPLC), human recombinant, expressed in E. coli

• 同義詞: Clara cell phospholipid-binding protein, Secretoglobin family 1A member 1, Urinary protein 1
• 分類程式碼代碼: 12352202
• NACRES: NA.32

屬性

• 產品名稱: UTERGLOBULIN human, recombinant, expressed in E. coli, ≥98% (SDS-PAGE), ≥98% (HPLC)
• 生物源: human
• 重組細胞: expressed in E. coli
• 化驗: ≥98% (HPLC); ≥98% (SDS-PAGE)
• 形狀: lyophilized
• 分子量: 8.0 kDa
• 包裝: pkg of 50 μg
• 雜質: endotoxin, tested
• UniProt登錄號: P11684
• 運輸包裝: wet ice
• 儲存溫度: −20°C
• 基因資訊: human ... SCGB1A1(7356)

描述

一般說明

Uteroglobin, also known as clara cell phospholipid-binding protein or CC10, is a member of the secretoglobin superfamily. It is secreted from nonciliated cells in the epithelial lining of bronchioles, also referred as Clara cells.[1][2] Uteroglobin is encoded by the gene mapped to human chromosome 11q12.2 – 13.1.[3] Recombinant Human Uteroglobin is an 8.0kDa homodimeric protein consisting of 142 amino acid residues.

生化／生理作用

Uteroglobin functions as an immunomodulatory and anti-inflammatory protein. Uteroglobin might play a vital role in regulation of airway inflammation.[2] Elevated level of uteroglobin has been observed in fallopian tubes of tubal ectopic pregnant women and in female patients with pelvic inflammatory disease.[4] Uteroglobin level is reduced in serum of asthmatic patients with a long duration of the disease.[2] Uteroglobin stimulates the growth of preimplantation blastocysts and it functions as a carrier and/or scavenger of progesterone, decreasing its toxicity to the early developing embryo. Uteroglobin has the capacity to prevent both chemotaxis and phagocytosis of monocytes and neutrophils.[3]

外觀

Lyophilized from 1 x PBS

重構

Centrifuge the vial prior to opening. Reconstitute in water to a concentration of 0.1-1.0 mg/ml. Do not vortex. This solution can be stored at 2-8°C for up to 1 week. For extended storage, it is recommended to further dilute in a buffer containing a carrier protein (example 0.1% BSA) and store in working aliquots at -20°C to -80°C.

安全資訊

• 儲存類別代碼: 11 - Combustible Solids
• 水污染物質分類（WGK）: WGK 3
• 閃點（°F）: Not applicable
• 閃點（°C）: Not applicable