SML1252

Treosulfan

≥98% (HPLC)

• 同義詞: (2S,3S)-Butanetetraol 1,4-dimesylate, (2S,3S)-Threitol 1,4-bismethanesulfonate, L-Threitol 1,4-bis(methanesulfonate), NSC 39069, Threosulphan, Treosulphan
• 經驗公式（希爾表示法）: C₆H₁₄O₈S₂
• CAS號碼: 299-75-2
• 分子量：: 278.30
• 分類程式碼代碼: 12352200
• NACRES: NA.77

屬性

• 品質等級: 100
• 化驗: ≥98% (HPLC)
• 形狀: powder
• 光學活性: [α]/D -4.9 to -5.9°, c = 1 in acetone
• 顏色: white to beige
• 溶解度: H₂O: 5 mg/mL, clear
• 儲存溫度: −20°C
• SMILES 字串: [S](=O)(=O)(OCC(O)C(O)CO[S](=O)(=O)C)C
• InChI: 1S/C6H14O8S2/c1-15(9,10)13-3-5(7)6(8)4-14-16(2,11)12/h5-8H,3-4H2,1-2H3
• InChI 密鑰: YCPOZVAOBBQLRI-UHFFFAOYSA-N

描述

生化／生理作用

Alkylating agent, anti-neoplastic agent

Treosulfan is a biofunctional alkylating agent.

Treosulfan is bifunctional alkylating agent.

Treosulfan/l-threitol-1,4-bis-methanesulfonate; dihydroxybusulfan; NSC 39069. It is a prodrug of a bifunctional alkylating cytotoxic agent.[1] Treosulfan can be activated non-enzymatically to two active epoxides. It is used to treat ovarian cancer.[2]

安全資訊

• 象形圖: GHS08
• 訊號詞: Danger
• 危險聲明: H340,H350,H361f
• 防範說明: P201 - P202 - P280 - P308 + P313 - P405 - P501
• 危險分類: Carc. 1A - Muta. 1B - Repr. 2
• 儲存類別代碼: 6.1C - Combustible acute toxic Cat.3 / toxic compounds or compounds which causing chronic effects
• 水污染物質分類（WGK）: WGK 3
• 閃點（°F）: Not applicable
• 閃點（°C）: Not applicable