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SML0936

Sigma-Aldrich

特立氟胺

≥98% (HPLC)

同義詞:

(Z)-2-氰基-3-羟基-N- [4-(三氟甲基)苯基]-2-丁烯酰胺, A 1726, A77-1726, A771726, HMR 1726, N-(4-三氟甲基苯基)-2-氰基-3-羟基克罗胺, SU 20, 氟酰胺

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About This Item

經驗公式(希爾表示法):
C12H9F3N2O2
CAS號碼:
分子量::
270.21
分類程式碼代碼:
12352200
NACRES:
NA.77

品質等級

化驗

≥98% (HPLC)

形狀

powder

顏色

white to beige

溶解度

DMSO: 5 mg/mL, clear (warmed)

儲存溫度

−20°C

InChI

1S/C12H9F3N2O2/c1-7(18)10(6-16)11(19)17-9-4-2-8(3-5-9)12(13,14)15/h2-5,18H,1H3,(H,17,19)/b10-7-

InChI 密鑰

UTNUDOFZCWSZMS-YFHOEESVSA-N

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應用

特立氟胺是一种二氢乳清酸脱氢酶 (DHODH) 抑制剂。

生化/生理作用

特立氟胺是一种可口服的抗炎免疫调节剂。阻断二氢乳清酸脱氢酶的活性,阻止嘧啶合成及 T、B 细胞增殖和功能。特立氟胺用于治疗风湿性关节炎,最近被批准用于多发性硬化症。

象形圖

Exclamation mark

訊號詞

Warning

危險聲明

危險分類

Acute Tox. 4 Oral

儲存類別代碼

11 - Combustible Solids

水污染物質分類(WGK)

WGK 3

閃點(°F)

Not applicable

閃點(°C)

Not applicable


分析證明 (COA)

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Bioactive small molecules for immune system signaling target identification/validation and antibiotics, antivirals, and antifungals offered.

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