SMB01008

Aschantin

≥90% (LC/MS-ELSD)

• 同義詞: (+)-Aschantin, 5-[(3S,3aR,6S,6aR)-6-(3,4,5-trimethoxyphenyl)-1,3,3a,4,6,6a-hexahydrofuro[3,4-c]furan-3-yl]-1,3-benzodioxole
• 經驗公式（希爾表示法）: C₂₂H₂₄O₇
• CAS號碼: 13060-15-6
• 分子量：: 400.42
• 分類程式碼代碼: 12352205
• NACRES: NA.25

屬性

• 生物源: plant
• 化驗: ≥90% (LC/MS-ELSD)
• 形狀: solid
• 分子量: 400.42
• 溶解度: water: slightly soluble
• 應用: metabolomics; vitamins, nutraceuticals, and natural products
• 儲存溫度: −20°C
• SMILES 字串: O1[C@@H]([C@@H]3[C@@H]([C@H](OC3)c4cc5c(cc4)OCO5)C1)c2cc(c(c(c2)OC)OC)OC
• InChI: 1S/C22H24O7/c1-23-18-7-13(8-19(24-2)22(18)25-3)21-15-10-26-20(14(15)9-27-21)12-4-5-16-17(6-12)29-11-28-16/h4-8,14-15,20-21H,9-11H2,1-3H3/t14-,15-,20+,21+/m0/s1
• InChI 密鑰: ONDWGDNAFRAXCN-VUEDXXQZSA-N

描述

一般說明

Aschantin, a bioactive lignan, is a natural product commonly available from Magnolia Sp, and Artemisia Sp. plants. This secondary metabolite derived from plant sources exhibits various biological activities such as anti-inflammatory, antioxidant, and anticancer activities.

應用

It is a natural product derived from plant source that finds application in compound screening libraries, metabolomics, phytochemical, and pharmaceutical research.

生化／生理作用

Aschantin has various biological activities including peroxynitrite scavenging capacity, inhibition of inducible NO synthetase, antiplasmodial activity, Ca²⁺-antagonistic activity, platelet activating factor-antagonistic activity, and chemo-preventative or therapeutic activity mediated via inhibition of mTOR kinase.

The anticancer activity of aschantin is achieved by inhibiting Akt, a protein that plays a crucial role in promoting cancer cell growth and proliferation. By blocking Akt, aschantin disrupts multiple signaling pathways that are essential for cancer cells to thrive and multiply. This disruption ultimately leads to the suppression of cancer cell proliferation, making it an effective strategy for combating cancer.

特點和優勢

• High quality compound suitable for multiple research applications
• Compatible with HPLC and mass spectrometry techniques

其他說明

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安全資訊

• 儲存類別代碼: 11 - Combustible Solids
• 水污染物質分類（WGK）: WGK 3
• 閃點（°F）: Not applicable
• 閃點（°C）: Not applicable