推薦產品
物種活性
human
技術
ELISA: suitable
assay range
inter-assay cv: <10%
intra-assay cv: <12%
運輸包裝
wet ice
儲存溫度
−20°C
基因資訊
human ... JAK2(3717)
一般說明
The antibody pair provided in this kit recognizes Human Tyrosine-Phosphorylated-JAK2. The JAK2 (Janus kinase 2) gene is mapped to human chromosome 9p24.1.[1]
應用
请参考Protocol了解详情。
生化／生理作用
Janus kinase 2 (JAK2) mediates epithelial-mesenchymal transition in hepatocellular carcinoma.[2] The JAK2/STAT3 signaling pathway is associated with tumor development in a number of cancer such as gastric cancer.[3] Mutation in the JAK2 gene is known to activate JAK2 receptor action even in the absence of ligand, inducing cell proliferation and opposing apoptosis.[4]
訊號詞
Warning
危險聲明
防範說明
危險分類
Met. Corr. 1
儲存類別代碼
8A - Combustible corrosive hazardous materials
閃點（°F）
Not applicable
閃點（°C）
Not applicable
CD 274 (PDL 1) and JAK 2 genomic amplifications in pulmonary squamous?cell and adenocarcinoma patients.
Clave S, et al.
Histopathology, 72(2), 259-269 (2018)
SIRT6 inhibits growth of gastric cancer by inhibiting JAK2/STAT3 pathway.
Zhou J, et al.
Oncology Reports, 38(2), 1059-1066 (2017)
The genetic basis of haematological cancers (2016)
Norcantharidin inhibits IL-6-induced epithelial?mesenchymal transition via the JAK2/STAT3/TWIST signaling pathway in hepatocellular carcinoma cells.
Gao Y, et al.
Oncology Reports, 38(2), 1224-1232 (2017)
Active Filters
我們的科學家團隊在所有研究領域都有豐富的經驗，包括生命科學、材料科學、化學合成、色譜、分析等.
聯絡技術服務
