PZ0129

CP-380736

≥98% (HPLC)

• 同義詞: 6,7-Bis(2-methoxyethoxy)-3,4-dihydroquinazolin-4-one, 6,7-Bis(2-methoxyethoxy)-4(3H)-quinazolinone, PF-00520893
• 經驗公式（希爾表示法）: C₁₄H₁₈N₂O₅
• CAS號碼: 179688-29-0
• 分子量：: 294.30
• MDL號碼: MFCD02678087
• 分類程式碼代碼: 51111800
• PubChem物質ID: 329823716
• NACRES: NA.77

屬性

• 化驗: ≥98% (HPLC)
• 形狀: powder
• 顏色: off-white to light tan
• 溶解度: DMSO: ≥10 mg/mL
• 儲存溫度: room temp
• SMILES 字串: COCCOc1cc2N=CNC(=O)c2cc1OCCOC
• InChI: 1S/C14H18N2O5/c1-18-3-5-20-12-7-10-11(15-9-16-14(10)17)8-13(12)21-6-4-19-2/h7-9H,3-6H2,1-2H3,(H,15,16,17)
• InChI 密鑰: PMQWTUWLIGJTQD-UHFFFAOYSA-N

描述

生化／生理作用

CP-380736 is an inhibitor of the epidermal growth factor receptor (EGFR). EGFR is a tyrosine kinase that activates MAPK, JNK, and Akt pathways, and is an important mediator of several types of cancer, including lung cancer and glioblastoma multiforme.

特點和優勢

This compound is a featured product for Kinase Phosphatase Biology research. Click here to discover more featured Kinase Phosphatase Biology products. Learn more about bioactive small molecules for other areas of research at sigma.com/discover-bsm.

安全資訊

• 儲存類別代碼: 11 - Combustible Solids
• 水污染物質分類（WGK）: WGK 3
• 閃點（°F）: Not applicable
• 閃點（°C）: Not applicable