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重要文件

P3636

Sigma-Aldrich

戊巴比妥

同義詞:

5-乙基-5-(1-甲基丁基)-2,4,6-三氧六氢嘧啶, 戊巴比妥

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About This Item

經驗公式(希爾表示法):
C11H18N2O3
CAS號碼:
分子量::
226.27
EC號碼:
MDL號碼:
分類程式碼代碼:
12352200
暫時無法取得訂價和供貨情況

藥物控制

USDEA Schedule II; Home Office Schedule 3; psychotrope (France); kontrollierte Droge in Deutschland; regulated under CDSA - not available from Sigma-Aldrich Canada

SMILES 字串

CCCC(C)C1(CC)C(=O)NC(=O)NC1=O

InChI

1S/C11H18N2O3/c1-4-6-7(3)11(5-2)8(14)12-10(16)13-9(11)15/h7H,4-6H2,1-3H3,(H2,12,13,14,15,16)

InChI 密鑰

WEXRUCMBJFQVBZ-UHFFFAOYSA-N

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象形圖

Skull and crossbonesHealth hazard

訊號詞

Danger

危險聲明

危險分類

Acute Tox. 3 Oral - Repr. 2 - STOT SE 3

標靶器官

Central nervous system

儲存類別代碼

6.1C - Combustible acute toxic Cat.3 / toxic compounds or compounds which causing chronic effects

水污染物質分類(WGK)

WGK 3

閃點(°F)

Not applicable

閃點(°C)

Not applicable

個人防護裝備

Eyeshields, Faceshields, Gloves, type P3 (EN 143) respirator cartridges


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分析證明 (COA)

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Naoe Okamura et al.
Neuropharmacology, 58(1), 166-172 (2009-07-07)
Neuropeptide S (NPS) and its cognate receptor were reported to mediate anxiolytic-like and arousal effects. NPS receptors are predominantly expressed in the brain, especially in limbic structures, including amygdala, olfactory nucleus, subiculum and retrosplenial cortex. In contrast, the NPS precursor
M Katayama et al.
Laboratory animals, 47(2), 122-126 (2013-04-09)
Pharmacokinetics of drugs may differ between small and large mammals (including humans); therefore, drug testing in animal models must be carefully designed. Sprague-Dawley rats were used in cardiac experiments, during which the lopinavir concentration in serum had to match human
Nassir Mansour et al.
Journal of neurosurgery. Pediatrics, 12(1), 37-43 (2013-05-07)
Barbiturates are widely used in the management of high intracranial pressure (ICP) caused by diffuse brain swelling. The cardiovascular, renal, and immunological side effects of these drugs limit them to last-line therapy. There are few published data regarding the role
Christa M Helms et al.
The Journal of pharmacology and experimental therapeutics, 331(1), 142-152 (2009-07-31)
The gamma-aminobutyric acid (GABA)(A) receptors mediating the discriminative stimulus effects of ethanol were studied by comparing the potency of ethyl-8-azido-5,6-dihydro-5-methyl-6-oxo-4H-imidazol(1,5-a)benzodiazepine-3-carboxylate (Ro15-4513) and ethyl 8-fluoro-5,6-dihydro-5-methyl-6-oxo-4H-imidazol(1,5-a)-benzodiazepine-3-carboxylate (flumazenil, Ro15-1788) to antagonize ethanol, pentobarbital (PB), and midazolam substitution for ethanol. Ro15-4513 has high affinity
Pentobarbital for refractory intracranial hypertension: time to "go retro"?
Paul M Shore
Pediatric critical care medicine : a journal of the Society of Critical Care Medicine and the World Federation of Pediatric Intensive and Critical Care Societies, 14(3), 323-324 (2013-03-07)

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