This product is nicotine free base and is provided in the form of a neat or pure liquid.
推薦產品
化驗
≥99% (GC)
形狀
liquid
光學活性
[α]20/D −169°(lit.)
顏色
yellow
折射率
n20/D 1.5265 (lit.)
溶解度
ethanol: 50 mg/mL
密度
1.010 g/mL at 20 °C (lit.)
SMILES 字串
CN1CCC[C@H]1c2cccnc2
InChI
1S/C10H14N2/c1-12-7-3-5-10(12)9-4-2-6-11-8-9/h2,4,6,8,10H,3,5,7H2,1H3/t10-/m0/s1
InChI 密鑰
SNICXCGAKADSCV-JTQLQIEISA-N
基因資訊
human ... CHRNA2(1135) , CHRNA3(1136) , CHRNA4(1137) , CHRNB2(1141) , CHRNB4(1143) , CYP2A6(1548) , KCNH1(3756)
mouse ... Chrna7(11441) , Chrnb1(11443)
rat ... Chrna1(79557) , Chrna2(170945) , Chrna4(25590) , Chrna7(25302) , Chrnb2(54239) , Chrnb4(25103)
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訊號詞
Danger
危險分類
Acute Tox. 1 Oral - Acute Tox. 2 Dermal - Acute Tox. 2 Inhalation - Aquatic Chronic 2 - Eye Dam. 1 - Skin Irrit. 2
儲存類別代碼
6.1A - Combustible acute toxic Cat. 1 and 2 / very toxic hazardous materials
水污染物質分類（WGK）
WGK 3
閃點（°F）
213.8 °F - closed cup
閃點（°C）
101 °C - closed cup
個人防護裝備
Eyeshields, Faceshields, Gloves, type ABEK (EN14387) respirator filter
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Is product N3876 (-)-Nicotine considered freebase nicotine or a nicotine salt dissolved in a carrier liquid
1 answer-
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Hi , How i want to measure the purity level of nicotine? Can refractive index or polarimeter use to measure level of impurity?
1 answer-
The measurement of purity in nicotine can be assessed using various analytical techniques. Refractive index and polarimetry are among the methods that can provide useful information. However, it's important to note that these techniques may not directly measure specific impurities but can be indicative of changes in the overall composition or characteristics of a substance. The purity of this product is determined by GC. Gas Chromatography (GC) is a widely used and effective method for assessing the purity of nicotine and detecting impurities. GC separates and analyzes components based on their volatility and interaction with a stationary phase.
Please access a Certificate of Analysis in the DOCUMENTATION section for reference:
https://www.sigmaaldrich.com/product/sigma/n3876#product-documentationHelpful?
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Hello, I would like to know the concentration of the nicotine in this liquid solution.
1 answer-
This product is a neat or pure liquid. Based on the density of 1.02 g/mL and the molecular weight of 162.2 g/mole, the calculated molar concentration is 6.3 M.
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How long is the nicotine stable if stored at room temperature? How long is it stable after being dssiolved and how should the solution be stored?
1 answer-
This compound is stored at room temperature, but is extremely sensitive to light, moisture, and oxygen. The product is a neat liquid and packaged in amber glass under argon to preserve stability. In the unopened container, the product is stable at least until the recommended retest date reported on the lot specific Certificate of Analysis. This date is typically 3 years from the quality release date. Factors such as light, humidity, and exposure to air will limit the shelf life after opening, It is recommended to prepare solutions fresh. The vial head space should be cleared with argon or nitrogen prior to closing. Increased darkening of the material is an indication of product degradation. Please see the link below to review a sample Certificate of Analysis:
https://www.sigmaaldrich.com/certificates/sapfs/PROD/sap/certificate_pdfs/COFA/Q14/N3876-BULKBCCK8089.pdfHelpful?
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what % of ethanol should be used to be solublized?
1 answer-
This product should be dissolved in 200-proof, pure ethanol.
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What is the concentration of Product N3876, (-)-Nicotine?
1 answer-
This product is not a solution. It is a liquid. The physical state of (-)-Nicotine is a liquid at room temperature. It has not been dissolved in any solvent at a specific concentration to prepare a solution. The density of (-)-Nicotine as a liquid at 20 °C is 1.010 g/mL.
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What is the Department of Transportation shipping information for this product?
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Transportation information can be found in Section 14 of the product's (M)SDS.To access the shipping information for this material, use the link on the product detail page for the product.
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How can Product N3876, (-)-Nicotine, be solublized?
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Product N3876, (-)-Nicotine, is soluble in ethanol. It is only miscible in water. We would recommend to solublized the product in ethanol to make a 1000x stock solution. This can then be diluted 1:1000 into aqueous buffer for use.
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What is the difference between Nicotine, Products N3876 and N0267?
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Prod. No. N3876 is the naturally occurring (-) isomer while Prod. No. N0267 is a mixture of the (+) and (-) isomers.
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What is the molarity of Product N3876, (-)-Nicotine?
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The molarity of (-)-Nicotine is 6.23 M based on a 100% pure compound with a density at 20 °C equal to 1.010 g/mL. If you multiply this density by 1000, you obtain g/L. If you divide g/L by the molecular weight of (-)-Nicotine which is 162.2 g/mole, you get moles per L which is molarity. [1.010 x 1000]/162.2 = 6.23 M.
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