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CHRNA1

cholinergic receptor, nicotinic, alpha 1 (muscle)

Synonyms:
ACHRA, ACHRD, CHRNA, CMS2A, FCCMS, SCCMS
Species:
Human CHRNA1 (1134), Mouse Chrna1 (11435), Rat Chrna1 (79557), dog CHRNA1 (403757), domestic guinea pig Chrna1 (100729588), cow CHRNA1 (338070), chicken CHRNA1 (395608), sheep CHRNA1 (101110120), Zebrafish chrna1 (30725), naked mole-rat Chrna1 (101715747)
UniProtKB ID:
P02708, B4DRV6, D3DPE8
Gene ID:
  • Human(1134) Summary: The muscle acetylcholine receptor consiststs of 5 subunits of 4 different types: 2 alpha subunits and 1 each of the beta, gamma, and delta subunits. This gene encodes an alpha subunit that plays a role in acetlycholine binding/channel gating. Alternatively spliced transcript variants encoding different isoforms have been identified. [provided by RefSeq, Nov 2012]
  • Mouse(11435) cholinergic receptor, nicotinic, alpha polypeptide 1 (muscle)
  • Rat(79557) cholinergic receptor, nicotinic, alpha 1 (muscle)
  • dog(403757) cholinergic receptor, nicotinic, alpha 1 (muscle)
  • domestic guinea pig(100729588) cholinergic receptor, nicotinic, alpha 1 (muscle)
  • cow(338070) cholinergic receptor, nicotinic, alpha 1 (muscle)
  • chicken(395608) cholinergic receptor, nicotinic, alpha 1 (muscle)
  • sheep(101110120) cholinergic receptor, nicotinic, alpha 1 (muscle)
  • Zebrafish(30725) cholinergic receptor, nicotinic, alpha polypeptide 1
  • naked mole-rat(101715747) cholinergic receptor, nicotinic, alpha 1 (muscle)

Custom & Knockdown Gene Products

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  • Custom Gene Products

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Small Molecule - Agonist

Product Number
Description
Species
N5511
(−)-Nicotine solution, 1.0 mg/mL, analytical standard, for drug analysis,
Species
human, mouse, rat
N3876
(−)-Nicotine, ≥99% (GC), liquid,
Species
human, mouse, rat
D1260
Decamethonium bromide, crystalline,
Species
human
D5891
1,1-Dimethyl-4-phenylpiperazinium iodide, ≥98% (TLC or titration),
Species
human, rat

Small Molecule - Antagonist

Product Number
Description
Species
297887
1-Octanol, anhydrous, ≥99%,
Species
mouse
293245
1-Octanol, suitable for HPLC, ≥99%,
Species
mouse
112615
1-Octanol, ReagentPlus®, 99%,
Species
mouse
W280003
1-Octanol, ≥98%, FCC, FG,
Species
mouse
W280011
1-Octanol, natural, ≥98%, FCC,
Species
mouse

Antibodies

Product Number
Description
Species Reactivity
Application
ZRB2584
Anti-CHRNA1/ACHRA Antibody, clone 2G22 ZooMAb® Rabbit Monoclonal, recombinant, expressed in HEK 293 cells,
Species Reactivity
human, mouse, rat
Application
affinity binding assay
immunocytochemistry
immunofluorescence
immunohistochemistry
western blot
SAB1402724
Monoclonal Anti-CHRNA1 antibody produced in mouse, clone 2G5, purified immunoglobulin, buffered aqueous solution,
Species Reactivity
human
Application
ELISA
MABN1618
Anti-Nicotinic Acetylchone Receptor alpha 1 Antibody, clone 7C8.2, clone 7C8.2, from mouse,
Species Reactivity
human, rat
Application
immunohistochemistry
western blot
AV34909
Anti-CHRNA1 (AB1) antibody produced in rabbit, affinity isolated antibody,
Species Reactivity
human
Application
western blot
AV34910
Anti-CHRNA1 (AB2) antibody produced in rabbit, affinity isolated antibody,
Species Reactivity
bovine, dog, guinea pig, horse, human, mouse, rabbit, rat
Application
western blot

Small Molecule - Blocker

Product Number
Description
Species
H0879
Hexamethonium bromide, ,
Species
human
T2265
Tetraethylammonium chloride, ≥98% (titration),
Species
human
H2138
Hexamethonium chloride, solid (hygroscopic),
Species
human
K3375
Kynurenic acid, ≥98%,
Species
rat, human

Small Molecule - Mixed Agonist/Antagonist

Product Number
Description
Species
N5511
(−)-Nicotine solution, 1.0 mg/mL, analytical standard, for drug analysis,
Species
human, mouse, rat
N3876
(−)-Nicotine, ≥99% (GC), liquid,
Species
human, mouse, rat

esiRNA

Product Number
Description
Species
EHU061451
MISSION® esiRNA, targeting human CHRNA1,
Species
human