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MAK110

Sigma-Aldrich

MTP 活性检测试剂盒

Supplied by Roar Biomedical, Inc.

同義詞:

MTTP活性检测试剂盒, 微粒体甘油三酯转运蛋白活性检测试剂盒

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About This Item

分類程式碼代碼:
12161503
NACRES:
NA.84
暫時無法取得訂價和供貨情況

用途

sufficient for 100 fluorometric tests

應用

pharmaceutical

檢測方法

fluorometric

相關疾病

cardiovascular diseases

儲存溫度

2-8°C

基因資訊

human ... MTTP(4547)

一般說明

微粒体甘油三酯转移蛋白(MTP),一种存在于肝脏中的膜结合蛋白,可在极低密度脂蛋白(VLDL)的组装和分泌中起到重要作用。[1]MTP对于肠内乳糜微粒的组装和分泌也是必需的。[1]该蛋白有助于甘油三酯(TG)、胆固醇酯(CE)和磷脂酰胆碱(PC)在磷脂表面之间的转移。 MTP基因中的突变可导致无β脂蛋白血症。[1][2]

應用

MTP活性检测试剂盒已被用于测量微粒体甘油三酯转移蛋白(MTP)的活性。[3]

特點和優勢

兼容高通量操作系统。

適合性

适用于测量细胞裂解液或组织匀浆液中微粒体[甘油三酯]转移蛋白(MTP)的活性,或用于筛选MTP活性抑制剂。

原則

MTP活性检测试剂盒是一种灵敏的均质荧光检测方法,可用于细胞裂解物或组织匀浆中中MTP活性的连续测量。该试剂盒包括能够检测 MTP 介导的中性脂质转移的专有底物。 这种转移活性导致荧光强度增加(λEx=465 nm/λEm=535 nm)。

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儲存類別代碼

10 - Combustible liquids


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