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MAK108

Sigma-Aldrich

磷脂转运蛋白活性检测试剂盒

Supplied by Roar Biomedical, Inc.

同義詞:

磷脂转运蛋白活性检测试剂盒

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About This Item

分類程式碼代碼:
12161503
NACRES:
NA.84
暫時無法取得訂價和供貨情況

用途

sufficient for 100 fluorometric tests

應用

pharmaceutical

檢測方法

fluorometric

相關疾病

cardiovascular diseases

儲存溫度

2-8°C

基因資訊

human ... PLTP(5360)

一般說明

Phospholipid transfer protein (PLTP) is a protein present in normal human plasma. PLTP transfers phospholipids among lipoproteins in plasma.

適合性

Suitable to determine Phospholipid transfer protein (PLTP) activity in plasma or serum (fresh or frozen) as well as other sources of PLTP.

原則

The PLTP Activity Assay Kit includes proprietary substrates to detect PLTP mediated transfer of fluorescent substrate. Transfer activity results in increased fluorescent emission intensity (λEx = 465 nm/λEm = 535 nm) from the assay.

儲存類別代碼

10 - Combustible liquids


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Ryan J Henderson et al.
Drug development and industrial pharmacy, 35(9), 1139-1146 (2009-04-22)
To investigate how different formulations of Amphotericin-B (Amp-B) affect the activity of phospholipid transfer protein (PLTP) when incubated with hyperlipidemic and normolipidemic plasma at physiological temperature (37 degrees C). Six hyperlipidemic and six normolipidemic plasma samples were collected and tested
Natacha Bellanger et al.
Arteriosclerosis, thrombosis, and vascular biology, 31(7), 1675-1681 (2011-04-30)
Low high-density lipoprotein (HDL) cholesterol levels are frequently observed in familial hypercholesterolemia (FH) and might be associated with functional alterations of HDL particles that may influence their efficaciousness in the reverse cholesterol transport pathway. We evaluated key steps of the
Axel Schlitt et al.
American journal of nephrology, 27(2), 138-143 (2007-02-20)
Phospholipid transfer protein (PLTP) is mainly involved in high-density lipoprotein (HDL) metabolism. The role of PLTP in atherogenesis is still controversial. We aimed to investigate PLTP activity in hemodialysis (HD) patients, a population which has an increased risk for the
Marta Marchesi et al.
British journal of pharmacology, 164(5), 1460-1468 (2011-04-14)
Besides a significant reduction of low-density lipoprotein (LDL) cholesterol, statins moderately increase high-density lipoprotein (HDL) levels. In vitro studies have indicated that this effect may be the result of an increased expression of apolipoprotein (apo)A-I, the main protein component of
F Briand et al.
European journal of clinical investigation, 36(4), 224-230 (2006-04-20)
The mechanisms involved in the decline of high-density lipoprotein (HDL) levels at a higher dose of atorvastatin have not yet been elucidated. We investigated the effects of atorvastatin on HDL-apolipoprotein (apo) A-I metabolism in dogs, a species lacking cholesteryl ester

Questions

1–2 of 2 Questions  
  1. Are products MAK107 and MAK108 compatible with mouse serum?

    1 answer
    1. Yes, but please be aware of possible sample hemolysis. Depending on the method of mouse sample collection, hemolysis may be common, which can interfere with fluorescence emission via color quenching.

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  2. What is the Department of Transportation shipping information for this product?

    1 answer
    1. Transportation information can be found in Section 14 of the product's (M)SDS.To access the shipping information for this material, use the link on the product detail page for the product.

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