推薦產品
用途
sufficient for 100 colorimetric or fluorometric tests
檢測方法
colorimetric
fluorometric
相關疾病
rheumatological diseases; gastrointestinal diseases; cardiovascular diseases
儲存溫度
−20°C
基因資訊
human ... XDH(7498)
mouse ... XDH(22436)
rat ... XDH(497811)
一般說明
黄嘌呤氧化酶催化次黄嘌呤依次氧化为黄嘌呤，黄嘌呤依次氧化为尿酸和过氧化氢。在人类和其他灵长类动物中，XO控制嘌呤分解代谢的最后一步，通常在肝脏和肠粘膜中发现。在啮齿动物中，XO在大多数组织中广泛表达。虽然血液中XO活性通常很低，但肝损伤会导致XO释放到血液中。XO可能参与痛风和心血管疾病的发病机制，XO活性或表达可能在这些情况下上调。
應用
黄嘌呤氧化酶活性检测试剂盒已用于测量血清样品中的黄嘌呤氧化酶。
適合性
适用于各种样品（包括组织、细胞和血清）中黄嘌呤氧化酶的测量
原則
黄嘌呤氧化酶活性检测试剂盒为测量各种生物样品中的XO活性提供了简单而直接的程序。XO活性由偶联酶测定法测定，结果比色（570 & # 160；nm）/荧光计（& # 955；ex = 535/& # 955；em = 587 & # 160nm）产品，与生成的过氧化氢成比例。XO的一个单位被定义为催化黄嘌呤在25 °C下每分钟氧化产生1.0 & # 160；& # 956；摩尔尿酸和过氧化氢的酶量。
儲存類別代碼
10 - Combustible liquids
分析證明 (COA)
輸入產品批次/批號來搜索 分析證明 (COA)。在產品’s標籤上找到批次和批號，寫有 ‘Lot’或‘Batch’.。
客戶也查看了
Probiotic therapy alleviates hyperuricemia in C57BL/6 mouse model.
Cao T, et al.
Biomedical Research, 28(5) (2017)
Shivangi Rastogi et al.
PLoS pathogens, 17(7), e1009712-e1009712 (2021-07-30)
Mycobacterium tuberculosis (Mtb) has evolved to evade host innate immunity by interfering with macrophage functions. Interleukin-1β (IL-1β) is secreted by macrophages after the activation of the inflammasome complex and is crucial for host defense against Mtb infections. We have previously
Neelam Malik et al.
BMC chemistry, 13(1), 53-53 (2019-08-07)
Hesperitin, a naturally occurring flavonoid was hybridized with phenolic acids to evaluate its potential to inhibit the activity of xanthine oxidase (XO), a key enzyme which catalyses xanthine to uric acid which is found to be associated with gout and
Ha Thi Nguyen et al.
PloS one, 16(6), e0253572-e0253572 (2021-07-01)
In the present study, in silico predictions and molecular docking were performed on five clerodane diterpenes (1-5) from Polyalthia longifolia seeds to evaluate their potential as xanthine oxidase (XO) inhibitors. The initial screening was conducted by target prediction using TargetNet
Neelam Malik et al.
BMC chemistry, 13(1), 71-71 (2019-08-07)
Xanthine oxidase is an important enzyme of purine catabolism pathway and has been associated directly in pathogenesis of gout and indirectly in many pathological conditions like cancer, diabetes and metabolic syndrome. In this research rutin, a bioactive flavonoid was explored
我們的科學家團隊在所有研究領域都有豐富的經驗，包括生命科學、材料科學、化學合成、色譜、分析等.
聯絡技術服務