跳轉至內容
Merck
全部照片(4)

重要文件

M9766

Sigma-Aldrich

4-甲基伞形酮 α- D -吡喃葡萄糖苷

α-glucosidase substrate, fluorogenic, ≥99% (TLC), powder

同義詞:

4-甲基伞形酮 α- D -葡萄糖苷

登入查看組織和合約定價


About This Item

經驗公式(希爾表示法):
C16H18O8
CAS號碼:
分子量::
338.31
Beilstein:
1690776
EC號碼:
MDL號碼:
分類程式碼代碼:
12352204
PubChem物質ID:
NACRES:
NA.32
暫時無法取得訂價和供貨情況

產品名稱

4-甲基伞形酮 α- D -吡喃葡萄糖苷, α-glucosidase substrate

描述

α-glucosidase substrate

化驗

≥99% (TLC)

形狀

powder

溶解度

pyridine: 50 mg/mL, clear, colorless to faintly yellow

儲存溫度

−20°C

SMILES 字串

CC1=CC(=O)Oc2cc(O[C@H]3O[C@H](CO)[C@@H](O)[C@H](O)[C@H]3O)ccc12

InChI

1S/C16H18O8/c1-7-4-12(18)23-10-5-8(2-3-9(7)10)22-16-15(21)14(20)13(19)11(6-17)24-16/h2-5,11,13-17,19-21H,6H2,1H3/t11-,13-,14+,15-,16+/m1/s1

InChI 密鑰

YUDPTGPSBJVHCN-JZYAIQKZSA-N

尋找類似的產品? 前往 產品比較指南

應用

4-甲基伞形基ǥ-D-吡喃葡糖苷已用于测定组织匀浆中的酸性 α-葡萄糖苷酶(GAA)活性。[1][1][2]

生化/生理作用

4-甲基伞形基ǥ-D-吡喃葡糖苷是 ǥ-葡萄糖苷酶的荧光底物。产物 4-甲基伞形花酯在荧光光谱中显示出 440nm 处的峰值。[3]

儲存類別代碼

11 - Combustible Solids

水污染物質分類(WGK)

WGK 3

閃點(°F)

Not applicable

閃點(°C)

Not applicable

個人防護裝備

Eyeshields, Gloves, type N95 (US)


從最近期的版本中選擇一個:

分析證明 (COA)

Lot/Batch Number

未看到正確版本?

如果您需要一個特定的版本,您可以透過批號來尋找特定憑證。

已經擁有該產品?

您可以在文件庫中找到最近購買的產品相關文件。

存取文件庫

Omid Motabar et al.
Analytical biochemistry, 390(1), 79-84 (2009-04-18)
Mutations in alpha-glucosidase cause accumulation of glycogen in lysosomes, resulting in Pompe disease, a lysosomal storage disorder. Small molecule chaperones that bind to enzyme proteins and correct the misfolding and mistrafficking of mutant proteins have emerged as a new therapeutic
Darin J Falk et al.
Molecular therapy : the journal of the American Society of Gene Therapy, 21(9), 1661-1667 (2013-06-05)
Pompe disease is a neuromuscular disease resulting from deficiency in acid α-glucosidase (GAA), results in cardiac, skeletal muscle, and central nervous system (CNS) pathology. Enzyme replacement therapy (ERT) has been shown to partially correct cardiac and skeletal muscle dysfunction. However
Phillip A Doerfler et al.
Human gene therapy, 27(1), 43-59 (2015-11-26)
Pompe disease is a progressive neuromuscular disorder caused by lysosomal accumulation of glycogen from a deficiency in acid alpha-glucosidase (GAA). Replacement of the missing enzyme is available by repeated protein infusions; however, efficacy is limited by immune response and inability
Ryoga Hamura et al.
Cancer science, 112(6), 2335-2348 (2021-05-02)
Lysosomal degradation plays a crucial role in the metabolism of biological macromolecules supplied by autophagy. The regulation of the autophagy-lysosome system, which contributes to intracellular homeostasis, chemoresistance, and tumor progression, has recently been revealed as a promising therapeutic approach for
Renata G K Leuschner et al.
Journal of AOAC International, 87(3), 604-613 (2004-08-04)
A standard method for the detection of Enterobacteriaceae was modified for the presumptive detection of Enterobacter sakazakii, and the modified method was validated in an interlaboratory trial with 16 laboratories from 8 European countries. The modification included a differential-elective medium

文章

Probiotics exhibit an inhibitory effect on pathogens, help prevent chronic intestinal inflammatory diseases or atopic syndromes, and support the immune system.

Questions

Reviews

No rating value

Active Filters

我們的科學家團隊在所有研究領域都有豐富的經驗,包括生命科學、材料科學、化學合成、色譜、分析等.

聯絡技術服務