跳轉至內容
Merck
全部照片(1)

重要文件

L2145

Sigma-Aldrich

L-亮氨酸-7-氨基-4-甲基香豆素 盐酸盐

fluorogenic, ≥98% (TLC), powder

同義詞:

H-L-Leu-AMC HCl

登入查看組織和合約定價


About This Item

經驗公式(希爾表示法):
C16H20N2O3 · HCl
CAS號碼:
分子量::
324.80
MDL號碼:
分類程式碼代碼:
12352204
PubChem物質ID:
NACRES:
NA.32
暫時無法取得訂價和供貨情況

產品名稱

L-亮氨酸-7-氨基-4-甲基香豆素 盐酸盐,

化驗

≥98% (TLC)

形狀

powder

溶解度

methanol: 50 mg/mL, clear, colorless to faintly yellow

螢光

λex 327 nm; λem 349 nm (pH 8.0)
λex 380 nm; λem 440 nm (Reaction product)

儲存溫度

−20°C

SMILES 字串

Cl.CC(C)C[C@H](N)C(=O)Nc1ccc2C(C)=CC(=O)Oc2c1

InChI

1S/C16H20N2O3.ClH/c1-9(2)6-13(17)16(20)18-11-4-5-12-10(3)7-15(19)21-14(12)8-11;/h4-5,7-9,13H,6,17H2,1-3H3,(H,18,20);1H/t13-;/m0./s1

InChI 密鑰

VCRXITKKWBOQRZ-ZOWNYOTGSA-N

一般說明

L-亮氨酸-7-酰胺基-4-甲基香豆素盐酸盐(Leu-AMC)是一种荧光肽基底物,用于测定亮氨酸氨肽酶活性,广泛存在于天然水生体系中。它是一种细菌蛋白水解酶。

應用

L-亮氨酸-7-酰胺基-4-甲基香豆素盐酸盐(Leu-AMC)用于作为底物类似物,测定亮氨酸氨肽酶活性。
L-亮氨酸-7-酰胺基-4-甲基香豆素盐酸盐已被用于:
  • 作为荧光土壤测定的底物[1]
  • 测定恶性疟原虫 M1 (PfA-M1)和 PfA-M17 酶的亮氨酸氨基肽酶活性[2]

儲存類別代碼

11 - Combustible Solids

水污染物質分類(WGK)

WGK 3

閃點(°F)

Not applicable

閃點(°C)

Not applicable

個人防護裝備

Eyeshields, Gloves, type N95 (US)


從最近期的版本中選擇一個:

分析證明 (COA)

Lot/Batch Number

未看到正確版本?

如果您需要一個特定的版本,您可以透過批號來尋找特定憑證。

已經擁有該產品?

您可以在文件庫中找到最近購買的產品相關文件。

存取文件庫

Vincent Tardy et al.
Journal of hazardous materials, 411, 125121-125121 (2021-04-17)
Pharmaceutical industry effluents are complex and highly variable in time. Assessing the efficiency of a pharmaceutical industry wastewater treatment plant (WWTP) and the resulting decrease in effluent toxicity and ecological risk is thus not straightforward. We set up an original
Enzyme activity responses to nutrient loading in subtropical wetlands
Penton CR and Newman S
Biogeochemistry, 84, 83-98 (2007)
Jisook Lee et al.
ChemMedChem, 16(1), 234-249 (2020-09-19)
Aminopeptidase N (APN/CD13) is a zinc-dependent ubiquitous transmembrane ectoenzyme that is widely present in different types of cells. APN is one of the most extensively studied metalloaminopeptidases as an anti-cancer target due to its significant role in the regulation of
Jian-Ming Huang et al.
Molecules (Basel, Switzerland), 24(24) (2019-12-19)
Acanthamoeba are a free-living protozoan whose pathogenic strain can cause severe human diseases, such as granulomatous encephalitis and keratitis. As such, the pathogenic mechanism between humans and Acanthamoeba is still unknown. In our previous study, we identified the secreted Acanthamoeba
M17 leucine aminopeptidase of the human malaria parasite Plasmodium vivax
Lee JY, et al.
Molecular and Biochemical Parasitology, 170, 45-48 (2010)

Questions

Reviews

No rating value

Active Filters

我們的科學家團隊在所有研究領域都有豐富的經驗,包括生命科學、材料科學、化學合成、色譜、分析等.

聯絡技術服務