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M4414

Sigma-Aldrich

肉豆蔻酰辅酶A 锂盐

Myristoyl coenzyme A lithium salt
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≥80.0% (HPLC), powder, protein myristoylation substrate

同義詞:

n - 肉豆蔻酰辅酶 A 锂盐

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About This Item

經驗公式(希爾表示法):
C35H62N7O17P3S · xLi+
CAS號碼:
分子量::
977.89 (free acid basis)
分類程式碼代碼:
12352202
NACRES:
NA.77
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產品名稱

肉豆蔻酰辅酶A 锂盐, ≥80.0%

品質等級

化驗

≥80.0%

儲存溫度

−20°C

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生化/生理作用

肉豆蔻酰基辅酶A是辅酶A和肉豆蔻酸酯的组合。它是N-肉豆蔻酰基转移酶催化的蛋白质肉豆蔻酰基化的底物。肉豆蔻酰化涉及将肉豆蔻酰基转移至蛋白氨基末端的甘氨酸残基上。[1]

特點和優勢

这种化合物是环核苷酸研究的特色产品。点击此处发现更多特色环核苷酸产品。在sigma.com/discover-bsm可了解更多关于生物活性小分子的其他研究领域。

基底

与辅酶A共价连接的长链脂肪酸(C14)。从头脂肪酸合成的底物。研究已显示,脂肪酰化可通过对GTP激活过程的成分进行直接变构修饰来阻止G蛋白相关的钙释放。

儲存類別代碼

11 - Combustible Solids

水污染物質分類(WGK)

WGK 3

閃點(°F)

Not applicable

閃點(°C)

Not applicable

個人防護裝備

Eyeshields, Gloves, type N95 (US)


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Signal Transduction - Single Cell Techniques, 327-327 (2008)
K E Rys-Sikora et al.
The Journal of biological chemistry, 269(50), 31607-31613 (1994-12-16)
A sensitive and specific GTP-activated Ca2+ translocation process induces rapid Ca2+ movements within cells and appears to reflect G protein-induced membrane fusion or junctional communication between discrete subpopulations of Ca(2+)-pumping organelles (Ghosh, T. K., Mullaney, J. M., Tarazi, F. I.
Functional significance of myristoyl moiety in N-myristoyl proteins.
L J Knoll et al.
Methods in enzymology, 250, 405-435 (1995-01-01)
F Dittrich et al.
European journal of biochemistry, 252(3), 477-485 (1998-04-18)
Elongation of long-chain fatty acids was investigated in yeast mutants lacking endogenous de novo fatty acid synthesis. In this background, in vitro fatty acid elongation was dependent strictly on the substrates malonyl-CoA, NADPH and a medium-chain or long-chain acyl-CoA primer
Yasmin ElMaghloob et al.
eLife, 10 (2021-01-14)
The ADP-ribosylation factor-like 3 (ARL3) is a ciliopathy G-protein which regulates the ciliary trafficking of several lipid-modified proteins. ARL3 is activated by its guanine exchange factor (GEF) ARL13B via an unresolved mechanism. BART is described as an ARL3 effector which

文章

Cyclic nucleotides like cAMP modulate cell function via PKA activation and ion channels.

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