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Merck
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重要文件

L7659

Sigma-Aldrich

Lewis-b tetrasaccharide

同義詞:

α-Fuc(1→2)-β-Gal-(1→3)-(α-Fuc-[1→4])-GlcNAc, Leb glycan

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About This Item

經驗公式（希爾表示法）:
C26H45NO19
分子量：:
675.63
MDL號碼:
MFCD01632618
分類程式碼代碼:
12352200
PubChem物質ID:
329817653
NACRES:
NA.32
暫時無法取得訂價和供貨情況

儲存溫度

−20°C

SMILES 字串

C[C@@H]1O[C@@H](O[C@@H]2[C@@H](O)[C@@H](O)[C@@H](CO)O[C@H]2O[C@@H]3[C@@H](NC(C)=O)C(O)O[C@H](CO)[C@H]3O[C@@H]4O[C@@H](C)[C@@H](O)[C@@H](O)[C@@H]4O)[C@@H](O)[C@H](O)[C@@H]1O

InChI

1S/C26H45NO19/c1-6-12(31)15(34)18(37)24(40-6)44-20-10(5-29)42-23(39)11(27-8(3)30)21(20)45-26-22(17(36)14(33)9(4-28)43-26)46-25-19(38)16(35)13(32)7(2)41-25/h6-7,9-26,28-29,31-39H,4-5H2,1-3H3,(H,27,30)/t6-,7-,9+,10+,11+,12+,13+,14-,15+,16+,17-,18-,19-,20+,21+,22+,23?,24-,25-,26-/m0/s1

InChI 密鑰

OXNGKCPRVRBHPO-VIXGDSECSA-N

相關類別

一般說明

The Lewis b (Leb) antigens are widely expressed in the proximal colon. During fetal development, Leb antigens are found throughout the colon, but after birth, they gradually diminish in the distal colon.[1]

應用

Lewis-b tetrasaccharide has been used to treat the P protein for complex crystal growth.[2]

生化／生理作用

The Lewis b (Leb) antigen reappearance is an excellent tumor marker for discriminating between malignant and benign tumors, and it can also be used in many cases of colon cancer.[1]

其他說明

Lewis-b human blood group determinant.

儲存類別代碼

11 - Combustible Solids

水污染物質分類（WGK）

WGK 3

閃點（°F）

Not applicable

閃點（°C）

Not applicable

個人防護裝備

Eyeshields, Gloves, type N95 (US)

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分析證明 (COA)

Lot/Batch Number
0000291552
SLCP1699
SLCF1684
SLCF1539
SLCD7642

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存取文件庫

Ning Hao et al.
Protein & cell, 6(2), 101-116 (2014-12-31)
Human noroviruses (huNoVs) recognize histo-blood group antigens (HBGAs) as attachment factors, in which genogroup (G) I and GII huNoVs use distinct binding interfaces. The genetic and evolutionary relationships of GII huNoVs under selection by the host HBGAs have been well
S Nishihara et al.
Glycobiology, 9(6), 607-616 (1999-05-25)
Lewis b (Leb) antigens are gradiently expressed from the proximal to the distal colon, i.e., they are abundantly expressed in the proximal colon, but only faintly in the distal colon. In the distal colon, they begin to increase at the

文章

Review of O-Linked Glycoproteins

O-Linked glycoproteins are usually large proteins with a molecular mass of >200 kDa. Glycosylation generally occurs in high-density clusters and may represent as much as 50-80% of the overall mass.

O- 連結糖蛋白回顧

O- 連結糖蛋白通常是分子質量 >200 kDa 的大型蛋白質。糖基化通常發生在高密度簇中，可能佔整體質量的 50-80%。

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