跳轉至內容
Merck
全部照片(2)

重要文件

L1294

Sigma-Aldrich

乳铁蛋白 人

recombinant, expressed in rice, Iron saturated, ≥90% (SDS-PAGE)

同義詞:

全转铁蛋白

登入查看組織和合約定價

選擇尺寸

100 MG
1 G


履行和交付延遲



選擇尺寸

變更視圖
100 MG
1 G

About This Item

MDL號碼:
分類程式碼代碼:
12352202
NACRES:
NA.25


履行和交付延遲


生物源

human

品質等級

重組細胞

expressed in rice

種類

for cell culture

化驗

≥90% (SDS-PAGE)
≥90% (biuret)

形狀

powder

技術

microbiological culture: suitable

雜質

≤10 EU/mg endotoxin

UniProt登錄號

儲存溫度

2-8°C

基因資訊

human ... LTF(4057)

尋找類似的產品? 前往 產品比較指南

應用

使用乳铁蛋白在铁限制培养基中培养变形链球菌[1]它用于检测乳铁蛋白是否会阻碍上皮细胞在体外的粘附。 [2]

生化/生理作用

乳铁蛋白是一种铁结合蛋白。在结构上与血浆铁转运蛋白转铁蛋白相似;但是乳铁蛋白对铁的亲和力要高得多(250 倍)。在初乳中含量非常丰富,少量也可见于泪液、唾液、粘液分泌物和中性粒细胞的次级颗粒中。由粘膜上皮和中性粒细胞组成,在炎症刺激下由这些细胞释放。细菌的生长被其隔离铁的能力所抑制,也通过其 N 端与脂多糖结合使细菌细胞壁通透性增加。乳铁蛋白可以通过与病毒包膜蛋白紧密结合来抑制病毒感染。这通过阻断结合域阻止了细胞与病毒的融合。乳铁蛋白似乎部分通过刺激中性粒细胞激活剂白细胞介素-8 的释放来激活宿主防御系统。还可能参与抗体和白细胞介素合成、淋巴细胞增殖和补体激活。

儲存類別代碼

11 - Combustible Solids

水污染物質分類(WGK)

WGK 3

閃點(°F)

Not applicable

閃點(°C)

Not applicable

個人防護裝備

Eyeshields, Gloves, type N95 (US)


從最近期的版本中選擇一個:

分析證明 (COA)

Lot/Batch Number

未看到正確版本?

如果您需要一個特定的版本,您可以透過批號來尋找特定憑證。

已經擁有該產品?

您可以在文件庫中找到最近購買的產品相關文件。

存取文件庫

Ling Tang et al.
Wound repair and regeneration : official publication of the Wound Healing Society [and] the European Tissue Repair Society, 18(1), 123-131 (2010-01-20)
Human lactoferrin (hLF), a glycoprotein of the transferrin family, has recently been shown to stimulate wound repair through its antimicrobial effect and inflammation modulation. A recent study with several non-skin cell lines indicated that hLF may also have a stimulatory
N Huang et al.
In vitro cellular & developmental biology. Animal, 44(10), 464-471 (2008-09-20)
Today there is a concern about the use of animal source proteins and peptides in cell culture applications due to potential contamination by adventitious infectious pathogens. Recombinant production of these proteins using a plant host provides a safe and cost
Erwann Rousseau et al.
Molecular pharmacology, 84(6), 888-898 (2013-10-01)
Previous studies on postmortem human brain tissue have shown that the iron-binding glycoprotein lactoferrin is upregulated in dopamine (DA) neurons resistant to degeneration in Parkinson disease (PD). To study how this could possibly relate to disease progression, we used midbrain
Xinyuan Lai et al.
iScience, 25(4), 104136-104136 (2022-03-29)
The global pandemic of COVID-19 caused by the severe acute respiratory syndrome coronavirus-2 (SARS-CoV-2) infection confers great threat to public health. Human breast milk is a complex nutritional composition to nourish infants and protect them from different kinds of infectious
Uxía Regueiro et al.
International journal of molecular sciences, 23(20) (2022-10-28)
Keratoconus (KC) is a corneal disorder whose etiology shares a close relationship with Lactoferrin (LTF) dysregulation and Toll-like Receptors 2 (TLR2) overexpression. This study shows how these two important biomarkers are clinically and molecularly interrelated, increasing knowledge about KC pathophysiology

Questions

1–3 of 3 Questions  
  1. what is the molecular weight of L1294, Lactoferrin human?

    1 answer
    1. The molecular weight of this product is approximately 80 kDa.

      Helpful?

  2. Do you have a recommendation for storage after dissolving in H2O? I cannot find any handling instructions online.

    1 answer
    1. The stability of this item has not been tested once it is in solution. It is recommended to make fresh before using the item.

      Helpful?

  3. What is the sequence of this product? Do you have the half (1-11) peptide product?

    1 answer
    1. L1294, Lactoferrin human, has the exact same amino acid sequence as the native protein. Unfortunately, we do not supply human lactoferrin peptide hLF1-11.

      Helpful?

Reviews

No rating value

Active Filters

我們的科學家團隊在所有研究領域都有豐富的經驗,包括生命科學、材料科學、化學合成、色譜、分析等.

聯絡技術服務