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I9271

Sigma-Aldrich

5-（碘乙酰胺基）荧光素

≥90% purity (HPLC), powder

同義詞:

5-IAF

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About This Item

經驗公式（希爾表示法）:
C22H14INO6
CAS號碼:
63368-54-7
分子量：:
515.25
Beilstein:
6543244
分類程式碼代碼:
12171500
PubChem物質ID:
329815467
NACRES:
NA.47
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產品名稱

5-（碘乙酰胺基）荧光素, ≥90% (HPLC)

化驗

≥90% (HPLC)

形狀

powder

技術

titration: suitable

顏色

yellow to orange

溶解度

DMSO: 5 mg/mL

螢光

λex 492 nm; λem 515 nm (Mercaptoethanol adduct)
λex 493 nm; λem 522 nm (pH 9.2)

應用

diagnostic assay manufacturing
hematology
histology

儲存溫度

−20°C

SMILES 字串

Oc1ccc2c(Oc3cc(O)ccc3C24OC(=O)c5cc(NC(=O)CI)ccc45)c1

InChI

1S/C22H14INO6/c23-10-20(27)24-11-1-4-15-14(7-11)21(28)30-22(15)16-5-2-12(25)8-18(16)29-19-9-13(26)3-6-17(19)22/h1-9,25-26H,10H2,(H,24,27)

InChI 密鑰

UATCLPJEZJKNHE-UHFFFAOYSA-N

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相關類別

一般說明

5-(碘乙酰氨基)荧光素是一种硫醇反应性荧光素衍生物。

應用

5-(碘乙酰氨基)荧光素用于合成荧光标记的细胞器（细胞核和核基质）、蛋白质和肽，包括酶。

儲存類別代碼

11 - Combustible Solids

水污染物質分類（WGK）

WGK 3

閃點（°F）

Not applicable

閃點（°C）

Not applicable

個人防護裝備

Eyeshields, Gloves, type N95 (US)

從最近期的版本中選擇一個：

分析證明 (COA)

Lot/Batch Number
MKCW3411
MKCV1777
MKCT9233
MKCV3491
MKCV3490

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Eukaryotic Cell, 9, 31-31 (2010)
D Chhabra et al.
Biophysical journal, 89(3), 1902-1908 (2005-07-05)
Actin is the principal component of microfilaments. Its assembly/disassembly is essential for cell motility, cytokinesis, and a range of other functions. Recent evidence suggests that actin is present in the nucleus where it may be involved in the regulation of
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Mitogen-activated protein kinase (MAPK) activation depends on a linear binding motif found in all MAPK kinases (MKK). In addition, the PB1 (Phox and Bem1) domain of MKK5 is required for extracellular signal regulated kinase 5 (ERK5) activation. We present the
Lisa M Landino et al.
The Journal of biological chemistry, 279(33), 35101-35105 (2004-06-09)
Alterations in the redox status of proteins have been implicated in the pathology of several neurodegenerative conditions including Alzheimer and Parkinson diseases. We report that peroxynitrite- and hydrogen peroxide-induced disulfides in the neuron-specific microtubule-associated proteins tau and microtubule-associated protein-2 are
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