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38132

Sigma-Aldrich

N-(5-荧光素基)马来酰亚胺

≥90% (HPLC), BioReagent, suitable for fluorescence

同義詞:

5-马来酰亚胺荧光素

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About This Item

經驗公式(希爾表示法):
C24H13NO7
CAS號碼:
分子量::
427.36
MDL號碼:
分類程式碼代碼:
12352111
PubChem物質ID:
NACRES:
NA.32
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產品線

BioReagent

化驗

≥90% (HPLC)

螢光

λex 490 nm; λem 518 nm in 0.1 M Tris pH 8.0

適合性

corresponds for coupling to thiols
suitable for fluorescence

儲存溫度

2-8°C

SMILES 字串

Oc1ccc2c(Oc3cc(O)ccc3C24OC(=O)c5cc(ccc45)N6C(=O)C=CC6=O)c1

InChI

1S/C24H13NO7/c26-13-2-5-17-19(10-13)31-20-11-14(27)3-6-18(20)24(17)16-4-1-12(9-15(16)23(30)32-24)25-21(28)7-8-22(25)29/h1-11,26-27H

InChI 密鑰

AYDAHOIUHVUJHQ-UHFFFAOYSA-N

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一般說明

N-(5-荧光素基)马来酰亚胺,又称荧光素-5-马来酰亚胺(FM),是一种荧光衍生化试剂。在衍生化反应过程中,pH值起着关键作用。[1]

應用

N-(5-荧光素基)马来酰亚胺或荧光素-5-马来酰亚胺可用作荧光生物传感器检测纳米颗粒。[2]

N-(5-荧光素基)马来酰亚胺(5-FM)可用于通过其硫醇基团对分子进行荧光标记,例如蛋白质和肽。

包裝

无底玻璃瓶。内含物在插入的融合锥体内。

象形圖

Exclamation mark

訊號詞

Warning

危險聲明

危險分類

Acute Tox. 4 Oral

儲存類別代碼

11 - Combustible Solids

水污染物質分類(WGK)

WGK 3

閃點(°F)

Not applicable

閃點(°C)

Not applicable

個人防護裝備

dust mask type N95 (US), Eyeshields, Gloves


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Vishakha Dastidar et al.
Journal of bacteriology, 189(15), 5550-5558 (2007-05-29)
In gram-negative bacteria, transporters belonging to the resistance-nodulation-cell division (RND) superfamily of proteins are responsible for intrinsic multidrug resistance. Haemophilus influenzae, a gram-negative pathogen causing respiratory diseases in humans and animals, constitutively produces the multidrug efflux transporter AcrB (AcrB(HI)). Similar
Linda Ojemyr et al.
Biochemistry, 48(10), 2173-2179 (2009-01-27)
Proton transport across biological membranes is a key step of the energy conservation machinery in living organisms, and it has been proposed that the membrane itself plays an important role in this process. In the present study we have investigated
Yumiko Takatsuka et al.
Proceedings of the National Academy of Sciences of the United States of America, 107(15), 6559-6565 (2010-03-10)
The AcrB trimeric multidrug efflux transporter of Escherichia coli pumps out a very wide spectrum of compounds. Although minocycline and doxorubicin have been cocrystallized within the large binding pocket in the periplasmic domain of the binding protomer, nothing is known
Di Zhou et al.
Macromolecular bioscience, 12(4), 465-474 (2012-04-13)
Branched poly(methoxy-PEG acrylate) and thermally responsive poly(methoxy-PEG acrylate)-block-poly(N-isopropylacrylamide) are synthesized by RAFT polymerization. After reduction, these polymers are fluorescently labeled by reacting the free thiol groups with N-(5-fluoresceinyl)maleimide. As shown by DLS, the labeled copolymer poly(methoxy-PEG acrylate)-block-poly(N-isopropylacrylamide) forms nanoparticles at
Karl A Hassan et al.
Biochemistry, 45(51), 15661-15669 (2006-12-21)
The staphylococcal TetA(K) tetracycline exporter is classified within the major facilitator superfamily of transport proteins and contains 14 alpha-helical transmembrane segments (TMS). Using cysteine-scanning mutagenesis, 27 amino acid residues across and flanking putative TMS 10 of the TetA(K) transporter were

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