跳轉至內容
Merck
全部照片(1)

文件

H7660

Sigma-Aldrich

Heregulin-β1(EGF 结构域) 人

≥98% (SDS-PAGE), recombinant, expressed in E. coli, lyophilized powder

同義詞:

HRG-β1

登入查看組織和合約定價


About This Item

MDL號碼:
分類程式碼代碼:
12352202
NACRES:
NA.32

生物源

human

品質等級

重組細胞

expressed in E. coli

化驗

≥98% (SDS-PAGE)

形狀

lyophilized powder

效力

<0.50 ng/mL

分子量

predicted mol wt 8 kDa

包裝

pkg of 10 and 50 μg

儲存條件

avoid repeated freeze/thaw cycles

雜質

endotoxin, tested

顏色

white

UniProt登錄號

儲存溫度

−20°C

基因資訊

human ... NRG1(3084)

生化/生理作用

ErbB3 和 ErbB4 受体酪氨酸激酶的生长因子配体。HRG 的结合导致受体二聚化和受体反式自磷酸化。磷酸化受体招募细胞信号蛋白,启动信号通路。

分析報告

它的生物活性通过其刺激在无血清条件下生长的人 MCF-7 细胞增殖的能力进行了测量。

儲存類別代碼

11 - Combustible Solids

水污染物質分類(WGK)

WGK 3

閃點(°F)

Not applicable

閃點(°C)

Not applicable

個人防護裝備

Eyeshields, Gloves, type N95 (US)


分析證明 (COA)

輸入產品批次/批號來搜索 分析證明 (COA)。在產品’s標籤上找到批次和批號,寫有 ‘Lot’或‘Batch’.。

已經擁有該產品?

您可以在文件庫中找到最近購買的產品相關文件。

存取文件庫

Neural grafts containing exosomes derived from Schwann cell-like cells promote peripheral nerve regeneration in rats.
Hu, et al.
Burns & trauma, 11, tkad013-tkad013 (2023)
Paul J Harrison et al.
Biological psychiatry, 60(2), 132-140 (2006-01-31)
Neuregulin 1 (NRG1) is a leading schizophrenia susceptibility gene. The NRG1 locus on chromosome 8p shows linkage to the disorder, and genetic association has been found between schizophrenia and various non-coding polymorphisms and haplotypes, especially at the 5' end of
Wei Tan et al.
The Journal of biological chemistry, 282(33), 24343-24351 (2007-06-15)
Neuregulin 1 (NRG1) is essential for the development and function of multiple organ systems, and its dysregulation has been linked to diseases such as cancer and schizophrenia. Recently, altered expression of a novel isoform (type IV) in the brain has
Shuji Wakatsuki et al.
Genes to cells : devoted to molecular & cellular mechanisms, 19(1), 66-77 (2013-11-22)
After peripheral nerve injury, Schwann cells gain a migratory phenotype and remodel their extracellular matrix to provide a supportive environment for axonal regeneration. The soluble neuregulin-1 isoform, that is, glial growth factor (GGF), is expressed in regenerating axons of injured
A M Addington et al.
Molecular psychiatry, 12(2), 195-205 (2006-10-13)
Childhood-onset schizophrenia (COS), defined as onset of psychosis by the age of 12, is a rare and malignant form of the illness, which may have more salient genetic influence. Since the initial report of association between neuregulin 1 (NRG1) and

我們的科學家團隊在所有研究領域都有豐富的經驗,包括生命科學、材料科學、化學合成、色譜、分析等.

聯絡技術服務