跳轉至內容
Merck
全部照片(5)

重要文件

G7879

Sigma-Aldrich

D-葡萄糖-6-磷酸 钠盐

≥98% (HPLC)

同義詞:

D(+)-葡糖醛糖6-磷酸 钠盐, G-6-P Na, 鲁氏酯

登入查看組織和合約定價


About This Item

經驗公式(希爾表示法):
C6H12NaO9P
CAS號碼:
分子量::
282.12
Beilstein:
5787568
EC號碼:
MDL號碼:
分類程式碼代碼:
12352201
PubChem物質ID:
NACRES:
NA.25
暫時無法取得訂價和供貨情況

生物源

synthetic (organic)

品質等級

化驗

≥98% (HPLC)

形狀

crystalline

技術

HPLC: suitable

顏色

white

有用的pH值範圍

4.0-5.0

mp

204 °C (dec.) (lit.)

溶解度

water: 50 mg/mL, clear, colorless to very faintly yellow

正離子痕跡

Na: 6.1-10.2% (anhydrous)

儲存溫度

room temp

SMILES 字串

[Na+].O[C@@H]1O[C@H](COP(O)([O-])=O)[C@@H](O)[C@H](O)[C@H]1O

InChI

1S/C6H13O9P.Na/c7-3-2(1-14-16(11,12)13)15-6(10)5(9)4(3)8;/h2-10H,1H2,(H2,11,12,13);/q;+1/p-1/t2-,3-,4+,5-,6-;/m1./s1

InChI 密鑰

ZALKNDISPIVVKC-WYRLRVFGSA-M

尋找類似的產品? 前往 產品比較指南

應用

D-葡萄糖-6-磷酸钠可用作结核分枝杆菌的能源。 [1]

生化/生理作用

在细胞中,当葡萄糖被己糖激酶或葡萄糖激酶磷酸化,或在糖原分解过程中磷酸葡萄糖变位酶将 1-磷酸葡萄糖转化时,会生成 D-葡萄糖 6-磷酸(G6P)。G6P 位于糖酵解和磷酸戊糖途径的起始阶段。当血糖水平高时,它也可以作为糖原储存。

注意

与二钠盐不同,它不吸湿,并且在室温下对大气湿度非常稳定。

其他說明

为了全面了解我们针对客户研究提供的各种单糖产品,建议您访问我们的碳水化合物分类页面。

儲存類別代碼

11 - Combustible Solids

水污染物質分類(WGK)

WGK 3

閃點(°F)

Not applicable

閃點(°C)

Not applicable

個人防護裝備

Eyeshields, Gloves, type N95 (US)


從最近期的版本中選擇一個:

分析證明 (COA)

Lot/Batch Number

未看到正確版本?

如果您需要一個特定的版本,您可以透過批號來尋找特定憑證。

已經擁有該產品?

您可以在文件庫中找到最近購買的產品相關文件。

存取文件庫

Iain J Abbott et al.
Antimicrobial agents and chemotherapy, 64(6) (2020-04-08)
There are limited treatment options for enterococcal urinary tract infections, especially vancomycin-resistant Enterococcus (VRE). Oral fosfomycin is a potential option, although limited data are available guiding dosing and susceptibility. We undertook pharmacodynamic profiling of fosfomycin against E. faecalis and E.
Iain J Abbott et al.
The Journal of antimicrobial chemotherapy, 75(4), 988-996 (2019-12-25)
To assess the antibacterial effects of a single 3 g oral fosfomycin dose on Escherichia coli and Klebsiella pneumoniae clinical isolates within a dynamic bladder infection model. An in vitro model simulating dynamic urinary fosfomycin concentrations was used. Target fosfomycin exposure
Iain J Abbott et al.
Antimicrobial agents and chemotherapy, 64(3) (2020-01-08)
Oral fosfomycin trometamol is licensed as a single oral dose for the treatment of uncomplicated urinary tract infections, with activity against multidrug-resistant uropathogens. The impact of interindividual variability in urinary concentrations on antimicrobial efficacy, and any benefit of giving multiple
Iain J Abbott et al.
Journal of microbiological methods, 171, 105861-105861 (2020-02-09)
The impact of the bladder environment on fosfomycin activity and treatment response is uncertain. Standard laboratory media does not reflect the biomatrix of urine, where limited nutritional factors are important for growth and antimicrobial kill rates. We compared fosfomycin activity
Calvin S Carter et al.
Cell metabolism, 32(4), 561-574 (2020-10-08)
Aberrant redox signaling underlies the pathophysiology of many chronic metabolic diseases, including type 2 diabetes (T2D). Methodologies aimed at rebalancing systemic redox homeostasis have had limited success. A noninvasive, sustained approach would enable the long-term control of redox signaling for

文章

沃伯格效應會增強腫瘤細胞中葡萄糖到乳酸的轉換,而不受氧氣水平的影響;自 1924 年起就開始影響癌症新陳代謝。

Warburg effect enhances glucose to lactate conversion in tumor cells, regardless of oxygen levels; impacting cancer metabolism since 1924.

條款

To measure glucose-6-phosphatase activity, the Taussky-Shorr method is used. This method is a spectrophotometric stop-rate determination assay that is measured at 660 nm.

To measure glucose-6-phosphate dehydrogenase activity, beta-nicotinamide adenine dinucleotide phosphate is used in a spectrophotometric rate determination assay at 340 nm.

在测定6-磷酸葡萄糖脱氢酶活性时,使用β-烟酰胺腺嘌呤二核苷酸磷酸在340 nm处通过分光光度法进行测定。

相關內容

Objective: To standardize a procedure for the enzymatic determination of Glucose-6-phosphatase activity

Questions

1–3 of 3 Questions  
  1. How can I determine the shelf life / expiration / retest date of this product?

    1 answer
    1. If this product has an expiration or retest date, it will be shown on the Certificate of Analysis (COA, CofA). If there is no retest or expiration date listed on the product's COA, we do not have suitable stability data to determine a shelf life. For these products, the only date on the COA will be the release date; a retest, expiration, or use-by-date will not be displayed.
      For all products, we recommend handling per defined conditions as printed in our product literature and website product descriptions. We recommend that products should be routinely inspected by customers to ensure they perform as expected.
      For products without retest or expiration dates, our standard warranty of 1 year from the date of shipment is applicable.
      For more information, please refer to the Product Dating Information document: https://www.sigmaaldrich.com/deepweb/assets/sigmaaldrich/marketing/global/documents/449/386/product-dating-information-mk.pdf

      Helpful?

  2. How is shipping temperature determined? And how is it related to the product storage temperature?

    1 answer
    1. Products may be shipped at a different temperature than the recommended long-term storage temperature. If the product quality is sensitive to short-term exposure to conditions other than the recommended long-term storage, it will be shipped on wet or dry-ice. If the product quality is NOT affected by short-term exposure to conditions other than the recommended long-term storage, it will be shipped at ambient temperature. As shipping routes are configured for minimum transit times, shipping at ambient temperature helps control shipping costs for our customers. For more information, please refer to the Storage and Transport Conditions document: https://www.sigmaaldrich.com/deepweb/assets/sigmaaldrich/marketing/global/documents/316/622/storage-transport-conditions-mk.pdf

      Helpful?

  3. May I know what is the recommended storage condition for the reconstituted working solution and the estimated shelf life for both the stock and the working solution?

    1 answer
    1. Unfortunately, the stability of the material in solution at the working concentration has not been determined. However, similar product 346764, α-D-Glucose-6-phosphate monosodium salt, states that aqueous stock solutions are stable for up to 6 weeks at -20°C.

      Helpful?

Reviews

No rating value

Active Filters

我們的科學家團隊在所有研究領域都有豐富的經驗,包括生命科學、材料科學、化學合成、色譜、分析等.

聯絡技術服務