E7879

β-雌二醇 17-醋酸酯

≥99%

• 同義詞: 1,3,5(10)-雌三烯-3,17β-二醇 17-醋酸酯, 3,17β-二羟基-1,3,5(10)-雌三烯 17-醋酸酯
• 經驗公式（希爾表示法）: C₂₀H₂₆O₃
• CAS號碼: 1743-60-8
• 分子量：: 314.42
• Beilstein: 2625732
• MDL號碼: MFCD00056537
• 分類程式碼代碼: 12352200
• PubChem物質ID: 24894658
• NACRES: NA.77

屬性

• 無菌: non-sterile
• 化驗: ≥99%
• 形狀: powder
• 溶解度: chloroform: 50 mg/mL, clear, colorless to faintly brownish-yellow
• 運輸包裝: ambient
• 儲存溫度: room temp
• SMILES 字串: CC(=O)O[C@H]1CC[C@H]2[C@@H]3CCc4cc(O)ccc4[C@H]3CC[C@]12C
• InChI: 1S/C20H26O3/c1-12(21)23-19-8-7-18-17-5-3-13-11-14(22)4-6-15(13)16(17)9-10-20(18,19)2/h4,6,11,16-19,22H,3,5,7-10H2,1-2H3/t16-,17-,18+,19+,20+/m1/s1
• InChI 密鑰: QAHOQNJVHDHYRN-SLHNCBLASA-N

描述

應用

β-Estradiol 17-acetate has been used in body burden analyses, to study the effect of triclosan on an estuarine fish.[1]

生化／生理作用

β-Estradiol is a steroid hormone involved in a number of organ functions. It is significantly associated with brain functions including neuroprotection, neurogenesis and synaptic plasticity.[2] β-Estradiol maintains bone homeostasis, and hence is preferred for osteoporosis therapy.[3] 17-β-Estradiol is the most active estrogen generated in our body.[4] During postmenopausal, 17-β-estradiol inhibits oxidative modification in low density lipoprotein. This indicates that estrogen replacement therapy might be useful in treating cardiovascular disease.[5]

特點和優勢

This compound is a featured product for ADME Tox research. Click here to discover more featured ADME Tox products. Learn more about bioactive small molecules for other areas of research at sigma.com/discover-bsm.

安全資訊

• 象形圖: GHS08,GHS09
• 訊號詞: Danger
• 危險聲明: H360FD,H410
• 防範說明: P202 - P273 - P280 - P308 + P313 - P391 - P405
• 危險分類: Aquatic Chronic 1 - Repr. 1B
• 儲存類別代碼: 6.1C - Combustible acute toxic Cat.3 / toxic compounds or compounds which causing chronic effects
• 水污染物質分類（WGK）: WGK 3
• 個人防護裝備: Eyeshields, Gloves, type P3 (EN 143) respirator cartridges