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文件

D8399

Sigma-Aldrich

达那唑

≥98% (TLC), powder, androgen receptor agonist

同義詞:

17β-羟基-2,4,17α-妊娠双烯-20-炔并[2,3-d]异恶唑, 2,4,17α-妊娠双烯-20-炔并[2,3-d]­异恶唑-17-醇

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About This Item

經驗公式(希爾表示法):
C22H27NO2
CAS號碼:
分子量::
337.46
EC號碼:
MDL號碼:
分類程式碼代碼:
51111800
PubChem物質ID:
NACRES:
NA.77

product name

达那唑, ≥98%

化驗

≥98%

形狀

powder

藥物控制

regulated under CDSA - not available from Sigma-Aldrich Canada

起源

Sanofi Aventis

SMILES 字串

CC12Cc3cnoc3C=C1CCC4C2CCC5(C)C4CC[C@@]5(O)C#C

InChI

1S/C22H27NO2/c1-4-22(24)10-8-18-16-6-5-15-11-19-14(13-23-25-19)12-20(15,2)17(16)7-9-21(18,22)3/h1,11,13,16-18,24H,5-10,12H2,2-3H3/t16?,17?,18?,20?,21?,22-/m0/s1

InChI 密鑰

POZRVZJJTULAOH-ZIKCMSSPSA-N

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生化/生理作用

达那唑是一种弱的雄性激素;垂体前叶抑制剂。

特點和優勢

该化合物是由 Sanofi Aventis开发。如需浏览其他药物开发的化合物和批准的药物/候选药物清单,请单击此处

包裝

无底玻璃瓶。内含物装在锥底内插管中。

象形圖

Health hazardExclamation mark

訊號詞

Warning

危險聲明

危險分類

Acute Tox. 4 Dermal - Acute Tox. 4 Inhalation - Repr. 2

儲存類別代碼

11 - Combustible Solids

水污染物質分類(WGK)

WGK 3

閃點(°F)

Not applicable

閃點(°C)

Not applicable

個人防護裝備

Eyeshields, Gloves, type P3 (EN 143) respirator cartridges


分析證明 (COA)

輸入產品批次/批號來搜索 分析證明 (COA)。在產品’s標籤上找到批次和批號,寫有 ‘Lot’或‘Batch’.。

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存取文件庫

E Hughes et al.
The Cochrane database of systematic reviews, (1)(1), CD000069-CD000069 (2007-01-27)
The synthetic androgen Danazol, was developed in the 1970's as a treatment for endometriosis. Its use was soon advocated in women with unexplained subfertility. Two randomised trials were subsequently conducted to assess the effectiveness of danazol in this population. The
V Selak et al.
The Cochrane database of systematic reviews, (4)(4), CD000068-CD000068 (2007-10-19)
Endometriosis is defined as the presence of endometrial tissue (stromal and glandular) outside the normal uterine cavity. Conventional medical and surgical treatments for endometriosis aim to remove or decrease the deposits of ectopic endometrium. The observation that hyper androgenic states
Terry Gernsheimer et al.
Blood, 121(1), 38-47 (2012-11-15)
A mild thrombocytopenia is relatively frequent during pregnancy and has generally no consequences for either the mother or the fetus. Although representing no threat in the majority of patients, thrombocytopenia may result from a range of pathologic conditions requiring closer
Hywel D Williams et al.
Journal of pharmaceutical sciences, 101(9), 3360-3380 (2012-05-31)
The Lipid Formulation Classification System Consortium is an industry-academia collaboration, established to develop standardized in vitro methods for the assessment of lipid-based formulations (LBFs). In this first publication, baseline conditions for the conduct of digestion tests are suggested and a
H Beaumont et al.
The Cochrane database of systematic reviews, (3)(3), CD001017-CD001017 (2007-07-20)
Heavy menstrual bleeding (HMB) is an important cause of ill health in pre menopausal women. Medical therapy, with the avoidance of possibly unnecessary surgery is an attractive treatment option, but there is considerable variation in practice and uncertainty about the

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