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C4431

Sigma-Aldrich

含腺嘌呤的柠檬酸-磷酸-葡萄糖溶液

同義詞:

CPD-A

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About This Item

分類程式碼代碼:
12161700
NACRES:
NA.25
暫時無法取得訂價和供貨情況

一般說明

含腺嘌呤的柠檬酸盐-磷酸盐-葡萄糖溶液 (CPDA) 是一种用于储存血液的抗凝剂和防腐剂。可将红细胞保存期限延长至 35 天。维持血小板活性。[1]使用 CPDA 可提高输血后可视性，改善血液中的葡萄糖和 ATP 水平。[2]

應用

含腺嘌呤的柠檬酸盐-磷酸盐-葡萄糖溶液已被用作心脏穿刺采血过程中的抗凝剂，[3] 转基因鸡蛋溶菌酶-卵清蛋白-Duffy (HOD) 小鼠 [4] 和人类。[5]

生化／生理作用

可用于全血的抗凝
建议的抗凝血剂:全血比为 1:9

相關產品

產品號碼
描述
訂價

儲存類別代碼

12 - Non Combustible Liquids

水污染物質分類（WGK）

WGK 1

閃點（°F）

Not applicable

閃點（°C）

Not applicable

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分析證明 (COA)

Lot/Batch Number
0000421395
0000421395
0000387191
0000346907
0000362204

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HyunJoo Park et al.
Scientific reports, 6, 34257-34257 (2016-10-05)
The functionality and viability of stored human red blood cells (RBCs) is an important clinical issue in transfusions. To systematically investigate changes in stored whole blood, the hematological properties of individual RBCs were quantified in blood samples stored for various
Krishnan MohanKumar et al.
Nature communications, 10(1), 3494-3494 (2019-08-04)
Necrotizing enterocolitis (NEC) is an idiopathic, inflammatory bowel necrosis of premature infants. Clinical studies have linked NEC with antecedent red blood cell (RBC) transfusions, but the underlying mechanisms are unclear. Here we report a neonatal murine model to investigate this
James C Keith et al.
Arthritis research & therapy, 7(4), R769-R776 (2005-07-01)
The human leukocyte antigen B27 (HLA-B27) transgenic rat is a model of human inflammatory bowel disease, rheumatoid arthritis and psoriasis. Studies of chronic inflammation in other rat models have demonstrated activation of the kallikrein-kinin system as well as modulation by
Measuring cell surface area and deformability of individual human red blood cells over blood storage using quantitative phase imaging
Park H, et al.
Scientific reports, 6(6), 34257-34257 (2016)
The storage of hard-packed red blood cells in citrate-phosphate-dextrose (CPD) and CPD-adenine (CPDA-1)
Beutler E and West C
Blood, 54(1), 280-284 (1979)
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  1. How is shipping temperature determined? And how is it related to the product storage temperature?

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    1. Products may be shipped at a different temperature than the recommended long-term storage temperature. If the product quality is sensitive to short-term exposure to conditions other than the recommended long-term storage, it will be shipped on wet or dry-ice. If the product quality is NOT affected by short-term exposure to conditions other than the recommended long-term storage, it will be shipped at ambient temperature. As shipping routes are configured for minimum transit times, shipping at ambient temperature helps control shipping costs for our customers. For more information, please refer to the Storage and Transport Conditions document: https://www.sigmaaldrich.com/deepweb/assets/sigmaaldrich/marketing/global/documents/316/622/storage-transport-conditions-mk.pdf

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  2. How can I determine the shelf life / expiration / retest date of this product?

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    1. If this product has an expiration or retest date, it will be shown on the Certificate of Analysis (COA, CofA). If there is no retest or expiration date listed on the product's COA, we do not have suitable stability data to determine a shelf life. For these products, the only date on the COA will be the release date; a retest, expiration, or use-by-date will not be displayed.
      For all products, we recommend handling per defined conditions as printed in our product literature and website product descriptions. We recommend that products should be routinely inspected by customers to ensure they perform as expected.
      For products without retest or expiration dates, our standard warranty of 1 year from the date of shipment is applicable.
      For more information, please refer to the Product Dating Information document: https://www.sigmaaldrich.com/deepweb/assets/sigmaaldrich/marketing/global/documents/449/386/product-dating-information-mk.pdf

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