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Merck
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文件

C0330

Sigma-Aldrich

Ciprofibrate

同義詞:

2-[p-(2,2-Dichlorocyclopropyl)phenoxy]-2-methylpropanoic acid

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About This Item

經驗公式(希爾表示法):
C13H14Cl2O3
CAS號碼:
分子量::
289.15
EC號碼:
MDL號碼:
分類程式碼代碼:
41116107
PubChem物質ID:
NACRES:
NA.77

形狀

powder

品質等級

儲存溫度

2-8°C

SMILES 字串

CC(C)(Oc1ccc(cc1)C2CC2(Cl)Cl)C(O)=O

InChI

1S/C13H14Cl2O3/c1-12(2,11(16)17)18-9-5-3-8(4-6-9)10-7-13(10,14)15/h3-6,10H,7H2,1-2H3,(H,16,17)

InChI 密鑰

KPSRODZRAIWAKH-UHFFFAOYSA-N

基因資訊

human ... PPARA(5465)

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生化/生理作用

Peroxisome proliferator-activated receptor α (PPARα) agonist

象形圖

Health hazard

訊號詞

Danger

危險聲明

防範說明

危險分類

Carc. 1B

儲存類別代碼

6.1C - Combustible acute toxic Cat.3 / toxic compounds or compounds which causing chronic effects

水污染物質分類(WGK)

WGK 3

閃點(°F)

Not applicable

閃點(°C)

Not applicable

個人防護裝備

Eyeshields, Gloves, type P3 (EN 143) respirator cartridges


分析證明 (COA)

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Karen G Calfee-Mason et al.
Food and chemical toxicology : an international journal published for the British Industrial Biological Research Association, 46(6), 2062-2073 (2008-03-14)
Peroxisome proliferators (PPs) are a diverse class of chemicals, which cause a dramatic increase in the size and number of hepatic peroxisomes in rodents and eventually lead to the development of hepatic tumors. Nuclear factor-kappaB (NF-kappaB) is a transcription factor
Wei Xie et al.
Archives of toxicology, 83(10), 909-924 (2009-06-23)
Perfluorooctanesulfonamides, such as N-ethyl perfluorooctanesulfonamidoethanol (N-EtFOSE), are large scale industrial chemicals but their disposition and toxicity are poorly understood despite significant human exposure. The hypothesis that subacute exposure to N-EtFOSE, a weak peroxisome proliferator, causes a redox imbalance in vivo
Chae Hwa Kwon et al.
Toxicology, 244(1), 13-24 (2007-12-18)
Peroxisome proliferator-activated receptor gamma (PPARgamma) agonists have been reported to induce apoptosis in a variety of cell types including renal proximal epithelial cells. However, the underlying mechanism of cell death induced by PPARgamma agonists has not been clearly defined in
Chuhan Chung et al.
Advances in experimental medicine and biology, 617, 591-597 (2008-05-24)
Pigment epithelium-derived factor (PEDF) is an endogenous antiangiogenic protein that also possesses antitumor activity. The mechanisms by which PEDF exerts its actions remains poorly understood. We sought to understand the role of PEDF in hepatocellular carcinoma (HCC), a hypervascular malignancy
Zakaria El Kebbaj et al.
Endocrinology, 150(3), 1192-1201 (2008-10-25)
Seasonal obesity and fasting-associated hibernation are the two major metabolic events governing hepatic lipid metabolism in hibernating mammals. In this process, however, the role of the nuclear receptor known as peroxisome proliferator-activated receptor (PPAR)-alpha has not been elucidated yet. Here

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