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About This Item
經驗公式(希爾表示法):
C13H20Cl2N2 · 2 HBr
CAS號碼:
分子量::
437.04
MDL號碼:
分類程式碼代碼:
12352200
PubChem物質ID:
NACRES:
NA.77
暫時無法取得訂價和供貨情況
推薦產品
品質等級
化驗
≥95% (HPLC)
形狀
powder
儲存條件
desiccated
顏色
white
溶解度
H2O: >5 mg/mL
儲存溫度
2-8°C
SMILES 字串
Br.Br.CN(C)CCN(C)CCc1ccc(Cl)c(Cl)c1
InChI
1S/C13H20Cl2N2.2BrH/c1-16(2)8-9-17(3)7-6-11-4-5-12(14)13(15)10-11;;/h4-5,10H,6-9H2,1-3H3;2*1H
InChI 密鑰
WOALTFHGLDVJHK-UHFFFAOYSA-N
應用
BD 1047二氢溴酸盐已被用作肝细胞癌细胞中sigma-1受体的拮抗剂。[1]
BD 1047是一种选择性推定的σ1受体拮抗剂,用于sigma受体研究,以帮助区分和表征sigma1受体与其他sigma受体亚型的功能和作用。BD 1047用于帮助定义σ1受体在神经过程中的作用。
訊號詞
Danger
危險聲明
危險分類
Eye Dam. 1 - Skin Irrit. 2 - STOT SE 3
標靶器官
Respiratory system
儲存類別代碼
11 - Combustible Solids
水污染物質分類(WGK)
WGK 3
閃點(°F)
Not applicable
閃點(°C)
Not applicable
Tao Bai et al.
Journal of cellular and molecular medicine, 23(11), 7349-7359 (2019-09-12)
Sigma-1 receptor (S1R) regulates reactive oxygen species (ROS) accumulation via nuclear factor erythroid 2-related factor 2 (NRF2), which plays a vital role in ferroptosis. Sorafenib is a strong inducer of ferroptosis but not of apoptosis. However, the mechanism of sorafenib-induced
Omar Vélez López et al.
Journal of neuroimmune pharmacology : the official journal of the Society on NeuroImmune Pharmacology, 14(2), 226-240 (2018-10-12)
Pathogenesis of HIV-associated neurocognitive disorders (HAND) is mediated through the infiltration of perivascular macrophages into the brain with the secretion of viral, neurotoxic and inflammatory proteins. One of these proteins is cathepsin B (CATB), a lysosomal cysteine protease that induces
Susmita Sil et al.
Molecular neurobiology, 56(5), 3576-3590 (2018-08-29)
Cocaine, a known psychostimulant, results in oxidative stress and inflammation. Recent studies from our group have shown that cocaine induces inflammation in glial cells. Our current study was aimed at investigating whether cocaine exposure could also induce inflammation in non-glial
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