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重要文件

B4261

Sigma-Aldrich

生物胞素

Biocytin

≥98% (TLC), suitable for drug transporter assays

同義詞:

Bct, Nε-(+)-生物素基-L-赖氨酸

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About This Item

經驗公式(希爾表示法):
C16H28N4O4S
CAS號碼:
分子量::
372.48
Beilstein:
97197
MDL號碼:
分類程式碼代碼:
12352209
PubChem物質ID:
NACRES:
NA.26
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產品名稱

生物胞素, ≥98% (TLC)

化驗

≥98% (TLC)

形狀

powder

光學活性

[α]20/D +53°, c = 1.05% in 0.1 M NaOH(lit.)

技術

drug transporter assay: suitable

顏色

white to off-white

mp

~245 °C (dec.) (lit.)

儲存溫度

−20°C

SMILES 字串

[H][C@]12CS[C@@H](CCCCC(=O)NCCCC[C@H](N)C(O)=O)[C@@]1([H])NC(=O)N2

InChI

1S/C16H28N4O4S/c17-10(15(22)23)5-3-4-8-18-13(21)7-2-1-6-12-14-11(9-25-12)19-16(24)20-14/h10-12,14H,1-9,17H2,(H,18,21)(H,22,23)(H2,19,20,24)/t10-,11-,12-,14-/m0/s1

InChI 密鑰

BAQMYDQNMFBZNA-MNXVOIDGSA-N

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應用

生物胞素被作为一种底物,研究生物素酶的特应性和动力学,用来检测生物素酶缺乏症,并且作为模型化合物研究细胞和组织的摄入机制。生物胞素用于标记神经元,中棘神经元和视神经。[1][2][3]

生化/生理作用

生物胞素是赖氨酸和生物素加成。[4]它被生物素酶水解,作用于肽链插入生物素或自由生物素。[5]生物胞素可用作辅酶。[1]

儲存類別代碼

11 - Combustible Solids

水污染物質分類(WGK)

WGK 3

閃點(°F)

Not applicable

閃點(°C)

Not applicable

個人防護裝備

Eyeshields, Gloves, type N95 (US)


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分析證明 (COA)

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Extraocular Source of Oligodendrocytes Contribute to Retinal Myelination and Optokinetic Responses in Zebrafish
Chen Tian
Investigative Ophthalmology & Visual Science, 57(4) (2016)
Vishwa Mohan et al.
The Journal of neuroscience : the official journal of the Society for Neuroscience, 39(32), 6233-6250 (2019-06-12)
Dendritic spines in the developing mammalian neocortex are initially overproduced and then eliminated during adolescence to achieve appropriate levels of excitation in mature networks. We show here that the L1 family cell adhesion molecule Close Homolog of L1 (CHL1) and
Rui Tian et al.
Theranostics, 8(3), 735-745 (2018-01-19)
Purpose: Radionuclide therapy directed against tumors that express somatostatin receptors (SSTRs) has proven effective for the treatment of advanced, low- to intermediate-grade neuroendocrine tumors in the clinic. In clinical usage, somatostatin peptide-based analogs, labeled with therapeutic radionuclides, provide an overall
Jeanne T Paz et al.
Nature neuroscience, 16(1), 64-70 (2012-11-13)
Cerebrocortical injuries such as stroke are a major source of disability. Maladaptive consequences can result from post-injury local reorganization of cortical circuits. For example, epilepsy is a common sequela of cortical stroke, but the mechanisms responsible for seizures following cortical
Justin N Siemian et al.
Scientific reports, 9(1), 12026-12026 (2019-08-21)
A pivotal role of the lateral hypothalamus (LH) in regulating appetitive and reward-related behaviors has been evident for decades. However, the contributions of LH circuits to other survival behaviors have been less explored. Here we examine how lateral hypothalamic neurons

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