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重要文件

15759

Sigma-Aldrich

Kolliphor P 188

同義詞:

聚(乙二醇)- 嵌段 - 聚(丙二醇)- 嵌段 - 聚(乙二醇), Lutrol F68, 泊洛沙姆188

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About This Item

CAS號碼:
MDL號碼:
分類程式碼代碼:
12352104
NACRES:
NA.25

形狀

solid

品質等級

分子量

~7680-9510 g/mol

成份

oxyethylene, 79.9-83.7%

雜質

≤0.25% ethylene glycol and diethylene glycol
≤0.4% total ash
≤1 ppm ethylene oxide
≤1.0% water
≤2 ppm arsenic traces
≤20 ppm heavy metals
≤5 ppm dioxan
≤5 ppm propylene oxide
50-150 ppm butylhydroxytoluene

燃燒殘留物

≤0.30%

顏色

APHA: ≤120, 50/50 in CH3OH

pH值

5.0-7.5 (100 g/L in H2O)
6.0-7.5 (25 g/L in H2O)

CMC

0.48 mM

轉變溫度

cloud point >100 °C

HLB

>24

SMILES 字串

O2C(C2)C.O1CC1

InChI

1S/C3H6O.C2H4O/c1-3-2-4-3;1-2-3-1/h3H,2H2,1H3;1-2H2

InChI 密鑰

RVGRUAULSDPKGF-UHFFFAOYSA-N

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應用


  • P 188在牙科制剂中的稳定作用:研究P188对smartCrystal牙科用橙皮苷工业浓缩液的稳定作用,发现其可提高制剂的长期稳定性,有牙科治疗意义(Romero et al., 2015)。

生化/生理作用

Poloxamer 188广泛用作增稠剂和凝胶粘合剂。

其他說明

Poloxamer 188是广泛的嵌段共聚物系列泊洛沙姆(poloxamer)的一种型号。

法律資訊

儲存類別代碼

11 - Combustible Solids

水污染物質分類(WGK)

WGK 1


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分析證明 (COA)

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A N Sklifas et al.
Biofizika, 57(2), 317-324 (2012-05-19)
The adsorption abilities of the perfluorocarbon emulsion stabilized by Proxanol 268 were investigated in vitro and in vivo. In vitro, the saturation point for the blood plasma proteins was nearly reached after five minutes of incubation of the emulsion with
Xijun Zhang et al.
Journal of Huazhong University of Science and Technology. Medical sciences = Hua zhong ke ji da xue xue bao. Yi xue Ying De wen ban = Huazhong keji daxue xuebao. Yixue Yingdewen ban, 31(6), 842-845 (2011-12-17)
This study examined the effect of P85 (a pluronic block copolymer) and microbubble (MB) ultrasound contrast agents under ultrasound irradiation on gene transfection and expression. The pEGFP plasmids that can encode enhanced green fluorescent protein (pEGFP) served as a report
Tsz Chung Lai et al.
Colloids and surfaces. B, Biointerfaces, 99, 27-37 (2011-10-18)
Polyplex particles formed with plasmid DNA (pDNA) and Pluronic P85-block-poly{N-[N-(2-aminoethyl)-2-aminoethyl]aspartamide} (P85-b-P[Asp(DET)]) demonstrated highly effective transfection ability compared to PEG-based block cationomer, PEG-b-P[Asp(DET)]. Ternary polyplexes comprising PEG-b-P[Asp(DET)], poly(ethylene oxide)-b-poly(propylene oxide)-b-poly(ethylene oxide)-b-P[Asp(DET)] (P(EPE)-b-P[Asp(DET)]) used as an analog of P85-b-P[Asp(DET)], and pDNA were
Wanhua Feng et al.
Colloids and surfaces. B, Biointerfaces, 105, 43-50 (2013-01-29)
The interaction between bacteria and surfaces is central to many environmental, industrial and medical applications. Surfactants are commonly used in these applications and can potentially influence the bacterium/surface interaction. The effect of surfactants upon bacterial cell surface thermodynamic properties was
Houjian Gong et al.
Langmuir : the ACS journal of surfaces and colloids, 28(38), 13590-13600 (2012-09-08)
The block polyethers PEO-PPO-ph-PPO-PEO (BPE) and PPO-PEO-ph-PEO-PPO (BEP) are synthesized by anionic polymerization using bisphenol A as initiator. Compared with Pluronic P123, the aggregation behaviors of BPE and BEP at an air/water interface are investigated by the surface tension and

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