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Merck
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P5556

Sigma-Aldrich

Poloxamer 188 溶液

10%, sterile-filtered, BioReagent, suitable for insect cell culture

同義詞:

Poloxamer 188溶液

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About This Item

CAS號碼:
MDL號碼:
分類程式碼代碼:
12161902
PubChem物質ID:
NACRES:
NA.75

描述

non-ionic

品質等級

無菌

sterile-filtered

產品線

BioReagent

分子量

average mol wt 8350

濃度

10%

技術

cell culture | insect: suitable

雜質

endotoxin, tested

CMC

0.04 mM

轉變溫度

cloud point ≥100

HLB

29

InChI

1S/C3H6O.C2H4O/c1-3-2-4-3;1-2-3-1/h3H,2H2,1H3;1-2H2

InChI 密鑰

RVGRUAULSDPKGF-UHFFFAOYSA-N

一般說明

泊咯沙姆 188(P188)是一种非离子型两亲性共聚物。它包括疏水性聚氧化丙烯的中心链,末端两侧为亲水性聚氧化乙烯。

應用

一种非离子共聚物表面活性剂

生化/生理作用

泊咯沙姆 188(P188)具有血液流变学、抗血栓、抗炎和细胞保护活性。它可以恢复和稳定膜屏障功能。P188还可抑制脂质过氧化,降低表面张力和疏水性细胞粘附。P-188 具有低毒性,可用于口服给药。

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儲存類別代碼

10 - Combustible liquids

水污染物質分類(WGK)

WGK 2

閃點(°F)

Not applicable

閃點(°C)

Not applicable

個人防護裝備

Eyeshields, Gloves, multi-purpose combination respirator cartridge (US)


分析證明 (COA)

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Kerwin Kwek Zeming et al.
Lab on a chip, 20(18), 3445-3460 (2020-08-15)
In vitro erythroid cultures from human hematopoietic stem cells produce immature red blood cells (RBCs) called reticulocytes, which are important for RBCs production, and are widely used in scientific studies of malaria pathology, hematological diseases and protein translation. However, in
Daniel Helman et al.
Cytometry. Part A : the journal of the International Society for Analytical Cytology, 85(2), 162-168 (2013-06-15)
We developed a membrane bound reporter and selection molecule for sorting by fluorescence activated cell sorting (FACS) of cells producing a protein of interest. This molecule is composed of a transmembrane (TM) domain, fused on its extracellular end to a
Rahul P Bakshi et al.
Nature communications, 9(1), 315-315 (2018-01-24)
Chemoprophylaxis is currently the best available prevention from malaria, but its efficacy is compromised by non-adherence to medication. Here we develop a long-acting injectable formulation of atovaquone solid drug nanoparticles that confers long-lived prophylaxis against Plasmodium berghei ANKA malaria in
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Nature communications, 11(1), 4061-4061 (2020-08-15)
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