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Merck
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重要文件

PHR1299

Supelco

Pamabrom

Pharmaceutical Secondary Standard; Certified Reference Material

同義詞:

Pamabrom, PAM

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About This Item

CAS號碼:
EC號碼:
分類程式碼代碼:
41116107
NACRES:
NA.24
暫時無法取得訂價和供貨情況

等級

certified reference material
pharmaceutical secondary standard

品質等級

agency

traceable to USP 1077708

API 家族

pamabrom

CofA

current certificate can be downloaded

技術

HPLC: suitable
gas chromatography (GC): suitable

應用

pharmaceutical (small molecule)

形式

neat

儲存溫度

2-30°C

InChI

1S/C7H7BrN4O2.C4H11NO/c1-11-4-3(9-6(8)10-4)5(13)12(2)7(11)14;1-4(2,5)3-6/h1-2H3,(H,9,10);6H,3,5H2,1-2H3

InChI 密鑰

ATOTUUBRFJHZQG-UHFFFAOYSA-N

一般說明

Pharmaceutical secondary standards for application in quality control, provide pharma laboratories and manufacturers with a convenient and cost-effective alternative to the preparation of in-house working standards.
Pamabrom is a weak diuretic which is used as an analgesic and an antihistamine for symptomatic control of the premenstrual syndrome. It typically assists in the reduction of bloating associated with premenstrual syndrome.[1]

應用

Pamabrom may be used as a pharmaceutical reference standard for the determination of the analyte in pharmaceutical formulations by chromatography techniques.[1][2][3]
These Secondary Standards are qualified as Certified Reference Materials. These are suitable for use in several analytical applications including but not limited to pharma release testing, pharma method development for qualitative and quantitative analyses, food and beverage quality control testing, and other calibration requirements.

分析報告

These secondary standards offer multi-traceability to the USP, EP (PhEur) and BP primary standards, where they are available.

其他說明

This Certified Reference Material (CRM) is produced and certified in accordance with ISO 17034 and ISO/IEC 17025. All information regarding the use of this CRM can be found on the certificate of analysis.

腳註

To see an example of a Certificate of Analysis for this material enter LRAA0585 in the slot below. This is an example certificate only and may not be the lot that you receive.

象形圖

Exclamation mark

訊號詞

Warning

危險聲明

危險分類

Acute Tox. 4 Oral

儲存類別代碼

11 - Combustible Solids

水污染物質分類(WGK)

WGK 3

閃點(°F)

Not applicable

閃點(°C)

Not applicable


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分析證明 (COA)

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Fixed drug eruptions and oral rechallenge.
K Kauppinen
Cleveland Clinic journal of medicine, 58(1), 64-65 (1991-01-01)
Guillermo Di Girolamo et al.
Expert opinion on pharmacotherapy, 5(3), 561-570 (2004-03-12)
Primary dysmenorrhoea is the most frequent gynaecological condition, with a prevalence of 40 - 90% in women within the reproductive age. It is characterised by cyclic pelvic pain related to menstrual period, vomiting and headache. As prostaglandins and leukotrienes appear
Rp-Lc and TLc Densitometric Determination of paracetamol and pamabrom in presence of Hazardous Impurity of paracetamol and Application to pharmaceuticals
El-Houssini OM
Analytical Chemistry Insights, 8, ACI-S12349 (2013)
Mario I Ortiz
European journal of obstetrics, gynecology, and reproductive biology, 152(1), 73-77 (2010-05-19)
To evaluate the prevalence, impact and treatment of primary dysmenorrhea among Mexican university students. A multiple-choice questionnaire was administered to 1539 students in six university programs: medicine, nursing, nutrition, dentistry, pharmacy and psychology. Data on the presence, severity, symptoms, treatment
Sunyoung Lee et al.
The journal of physical chemistry. B, 117(31), 9233-9240 (2013-07-16)
Epithelial ovarian cancer cells enhance their ability to migrate and invade through the epithelial-mesenchymal transition (EMT), resulting in cell seeding and metastasis in the peritoneal cavity and onto adjacent organ surfaces. It has been speculated that cytoskeletal dynamics, such as

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