推薦產品
等級
pharmaceutical primary standard
API 家族
deferoxamine
製造商／商標名
EDQM
應用
pharmaceutical (small molecule)
形式
neat
SMILES 字串
CS(O)(=O)=O.CC(=O)N(O)CCCCCNC(=O)CCC(=O)N(O)CCCCCNC(=O)CCC(=O)N(O)CCCCCN
InChI
1S/C25H48N6O8.CH4O3S/c1-21(32)29(37)18-9-3-6-16-27-22(33)12-14-25(36)31(39)20-10-4-7-17-28-23(34)11-13-24(35)30(38)19-8-2-5-15-26;1-5(2,3)4/h37-39H,2-20,26H2,1H3,(H,27,33)(H,28,34);1H3,(H,2,3,4)
InChI 密鑰
IDDIJAWJANBQLJ-UHFFFAOYSA-N
尋找類似的產品？ 前往 產品比較指南
一般說明
本品按现行药典规定交付。所有为支持本产品而提供的信息，包括SDS和任何产品信息单均由药典颁发机构制定并发布。 如需进一步信息和支持，请访问现行药典网站。
應用
甲磺酸去铁胺EP参考标准品的预期用途是欧洲药典规定的实验室测试。
生化／生理作用
一种铁螯合剂，常用于研究细胞增殖和凋亡。 体外 和 体内 实验均显示其对血管平滑肌细胞具有抗增殖作用，并抑制G1期细胞的增殖。 据报道，它也诱导p53。 通过螯合铁诱导HL-60细胞凋亡。 经过1μM去铁胺处理48小时后，DNA明显断裂。 细胞经0.1μM去铁胺处理仅24小时后发生凋亡;48小时后观察到核坍塌。 一些研究表明，它具有抗氧化性能，并保护细胞免受H2O2诱导的损伤。
一种铁螯合剂，常用于研究细胞增殖和凋亡。据报道，它也诱导p53。
包裝
本品按照现行药典要求提供。有关当前单位数量，请见EDQM 参考目录。
其他說明
可能适用相应的销售限制。
儲存類別代碼
11 - Combustible Solids
水污染物質分類（WGK）
WGK 2
閃點（°F）
Not applicable
閃點（°C）
Not applicable
客戶也查看了
Meredith Corley et al.
Molecular cell, 80(5), 903-914 (2020-11-27)
Discovering the interaction mechanism and location of RNA-binding proteins (RBPs) on RNA is critical for understanding gene expression regulation. Here, we apply selective 2'-hydroxyl acylation analyzed by primer extension (SHAPE) on in vivo transcripts compared to protein-absent transcripts in four human
Xueping Guo et al.
PloS one, 9(4), e94156-e94156 (2014-04-17)
Hyaluronidases are a family of enzymes that degrade hyaluronic acid (hyaluronan, HA) and widely used in many fields. A hyaluronidase producing bacteria strain was screened from the air. 16S ribosomal DNA (16S rDNA) analysis indicated that the strain belonged to
Yudan Chi et al.
Science (New York, N.Y.), 369(6501), 276-282 (2020-07-18)
The tumor microenvironment plays a critical regulatory role in cancer progression, especially in central nervous system metastases. Cancer cells within the cerebrospinal fluid (CSF)-filled leptomeninges face substantial microenvironmental challenges, including inflammation and sparse micronutrients. To investigate the mechanism by which
Cindy A Ryan et al.
Toxicological sciences : an official journal of the Society of Toxicology, 178(1), 88-103 (2020-10-24)
A peptide reactivity assay with an activation component was developed for use in screening chemicals for skin sensitization potential. A horseradish peroxidase-hydrogen peroxide (HRP/P) oxidation system was incorporated into the assay for characterizing reactivity of hapten and pre-/prohapten sensitizers. The
Yoshiaki Tsuji
PloS one, 15(7), e0235563-e0235563 (2020-07-10)
Western blotting has been widely used for investigation of protein expression, posttranslational modifications, and interactions. Because western blotting usually involves heat-denaturation of samples prior to gel loading, clarification of detailed procedures for sample preparation have been omitted or neglected in
Active Filters
我們的科學家團隊在所有研究領域都有豐富的經驗，包括生命科學、材料科學、化學合成、色譜、分析等.
聯絡技術服務
