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C3250000

环磷酰胺

European Pharmacopoeia (EP) Reference Standard

同義詞:

环磷酰胺 一水合物, 2-[双(2-氯乙基)氨基]四氢-2H-1,3,2-噁磷-2-氧化物, Cytoxan

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About This Item

經驗公式(希爾表示法):
C7H15Cl2N2O2P · H2O
CAS號碼:
分子量::
279.10
Beilstein:
4678992
MDL號碼:
分類程式碼代碼:
41116107
PubChem物質ID:
NACRES:
NA.24

等級

pharmaceutical primary standard

API 家族

cyclophosphamide

製造商/商標名

EDQM

mp

49-51 °C (lit.)

應用

pharmaceutical (small molecule)

格式

neat

儲存溫度

2-8°C

SMILES 字串

[H]O[H].ClCCN(CCCl)P1(=O)NCCCO1

InChI

1S/C7H15Cl2N2O2P.H2O/c8-2-5-11(6-3-9)14(12)10-4-1-7-13-14;/h1-7H2,(H,10,12);1H2

InChI 密鑰

PWOQRKCAHTVFLB-UHFFFAOYSA-N

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一般說明

本品按现行药典规定交付。所有为支持本产品而提供的信息,包括SDS和任何产品信息单均由药典颁发机构制定并发布。如需进一步信息和支持,请访问现行药典网站。

應用

环磷酰胺EP参考标准品的预期用途是欧洲药典规定的实验室测试。

生化/生理作用

环磷酰胺是一种广泛用于癌症化疗的具有细胞毒性的氮芥衍生物。它可与 DNA 交联、导致链断裂并诱导突变。其临床活性与乙醛脱氢酶 1 (ALDH1) 的活性降低相关。

包裝

本品按照现行药典要求提供。有关当前单位数量,请见EDQM 参考目录

其他說明

可能会涉及到销售限制。

象形圖

Skull and crossbonesHealth hazard

訊號詞

Danger

危險分類

Acute Tox. 3 Oral - Carc. 1B - Muta. 1B - Repr. 1A

儲存類別代碼

6.1C - Combustible acute toxic Cat.3 / toxic compounds or compounds which causing chronic effects

水污染物質分類(WGK)

WGK 3


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