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重要文件

70709

Sigma-Aldrich

羟基四氢嘧啶

≥95% (HPLC)

同義詞:

(4S,5S)-5-羟基-2-甲基-1,4,5,6-四氢嘧啶-4-羧酸, THP(A)

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About This Item

經驗公式(希爾表示法):
C6H10N2O3
CAS號碼:
分子量::
158.16
MDL號碼:
分類程式碼代碼:
24112111
PubChem物質ID:
NACRES:
NA.21
暫時無法取得訂價和供貨情況

品質等級

化驗

≥95% (HPLC)

形狀

solid

SMILES 字串

CC1=N[C@@H]([C@@H](O)CN1)C(O)=O

InChI

1S/C6H10N2O3/c1-3-7-2-4(9)5(8-3)6(10)11/h4-5,9H,2H2,1H3,(H,7,8)(H,10,11)/t4-,5-/m0/s1

InChI 密鑰

KIIBBJKLKFTNQO-WHFBIAKZSA-N

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其他說明

酶和生物大分子的稳定剂[1][2][3]

儲存類別代碼

11 - Combustible Solids

水污染物質分類(WGK)

WGK 1

閃點(°F)

Not applicable

閃點(°C)

Not applicable

個人防護裝備

dust mask type N95 (US), Eyeshields, Gloves


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分析證明 (COA)

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Stanislav Obruca et al.
Applied microbiology and biotechnology, 100(3), 1365-1376 (2015-11-23)
Poly(3-hydroxybutyrate) (PHB) is a common carbon- and energy-storage compound simultaneously produced and degraded into its monomer 3-hydroxybutyrate (3HB) by numerous bacteria and Archae in a metabolic pathway called the PHB cycle. We investigated 3HB as a chemical chaperone capable of
Marc Benjamin Hahn et al.
Physical chemistry chemical physics : PCCP, 22(13), 6984-6992 (2020-03-20)
Ectoine is a small zwitterionic osmolyte and compatible solute, which does not interfere with cell metabolism even at molar concentrations. Plasmid DNA (pUC19) was irradiated with ultraviolet radiation (UV-C at 266 nm) under quasi physiological conditions (PBS) and in pure
Cuixia Guo et al.
Analytical biochemistry, 548, 109-114 (2018-03-03)
The Fe(II)/2-oxoglutarate-dependent dioxygenases (2-OGDs) catalyze the oxidation of substrates ranging from small molecules to large biomolecules with concomitant oxidation of co-substrate (2-oxoglutarate) into succinate. In the present study, we reported a coupled colorimetric assay that can be generally applied to
M.D. Vangala et al.
Bioforum, 23, 760-760 (2000)
Wei-Chuan Chen et al.
Journal of bioscience and bioengineering, 128(3), 332-336 (2019-04-03)
Hydroxyectoine, an ectoine derivative, is the most common compatible solute in halophilic microorganisms for resisting harsh environments. Compatible solutes can be utilized in fields such as cosmetics, medicine, and biochemistry. Moderately halophilic microorganisms produce much less hydroxyectoine as compared with

Questions

  1. what is Hydroxyectoine used for? can i use it stabilize multiple antibodies in a dry format with polyols

    1 answer
    1. Hydroxyectoin is an ectoine used by many halophilic microorganisms to protect themselves against the extreme salt and temperature conditions in their natural environment. Ectoines have been shown to stabilize proteins, nucleic acids, membranes, and cells. They do not interfere with enzymatic and binding reactions and are highly compatible with cell metabolism.

      Please see the datasheet below for more information:
      https://www.sigmaaldrich.com/deepweb/assets/sigmaaldrich/product/documents/398/586/70709dat.pdf

      Please see the link below to review a publication that may be helpful.
      https://www.sciencedirect.com/science/article/pii/S0301462214001409
      https://pubs.acs.org/doi/full/10.1021/acs.molpharmaceut.0c00395
      https://www.sigmaaldrich.com/search/70709?focus=papers&page=1&perpage=30&sort=relevance&term=70709&type=citation_search

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