Involved in vasodilator actions of kinins such as bradykinin. Inhibits MAP kinase in rat mesangial cells (IC50 = 25-50 µM). Regulates the activity of adenylate cyclase via G-protein coupled receptors.
生化/生理作用
Cell permeable: no
Primary Target Involved in vasodilator actions of kinins such as bradykinin
Product does not compete with ATP.
Reversible: no
Target IC50: 25-50 µM inhibiting MAP kinase in rat mesangial cells
警告
Toxicity: Harmful (C)
其他說明
Li, X., et al. 1995. Am. J. Physiol.269, C986. Kessler, W., et al. 1992. Exp. Brain Res.91, 467.
法律資訊
CALBIOCHEM is a registered trademark of Merck KGaA, Darmstadt, Germany
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