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444225

Sigma-Aldrich

MMP-3 Inhibitor II

The MMP-3 Inhibitor II, also referenced under CAS 161314-17-6, controls the biological activity of MMP-3. This small molecule/inhibitor is primarily used for Protease Inhibitors applications.

同義詞:

MMP-3 Inhibitor II, N-Isobutyl-N-(4-methoxyphenylsulfonyl)-glycylhydroxamic Acid, NNGH

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About This Item

經驗公式(希爾表示法):
C13H20N2O5S
CAS號碼:
分子量::
316.37
MDL號碼:
分類程式碼代碼:
12352200
NACRES:
NA.77

品質等級

化驗

≥98% (TLC)

形狀

solid

製造商/商標名

Calbiochem®

儲存條件

OK to freeze

顏色

white

溶解度

DMSO: 30 mg/mL
ethanol: 8 mg/mL

運輸包裝

ambient

儲存溫度

10-30°C

一般說明

A cell-permeable, potent inhibitor of human MMP-3 (stromelysin; Ki = 130 nM).
A potent and cell-permeable inhibitor of human MMP-3 (Ki = 130 nM).

生化/生理作用

Cell permeable: yes
Primary Target
human MMP-3
Product does not compete with ATP.
Reversible: no
Target Ki: 130 nM against human MMP-3

警告

Toxicity: Standard Handling (A)

重構

Following reconstitution, aliquot and freeze (-20°C). Stock solutions are stable for up to 6 months at -20°C.

其他說明

Kato, N., et al. 2002. Genome Informatics13, 272.
MacPherson, L.J., et al. 1997. J. Med. Chem. 40, 2525.

法律資訊

CALBIOCHEM is a registered trademark of Merck KGaA, Darmstadt, Germany

儲存類別代碼

11 - Combustible Solids

水污染物質分類(WGK)

WGK 3

閃點(°F)

Not applicable

閃點(°C)

Not applicable


分析證明 (COA)

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Angelika K Lemke et al.
Cell and tissue research, 340(1), 179-188 (2010-03-11)
Pro-inflammatory cytokines induce meniscal matrix degradation and inhibition of endogenous repair mechanisms, but the pathogenic mechanisms behind this are mostly unknown. Therefore, we investigated details of interleukin-1 (IL-1alpha)-induced aggrecan turnover in mature meniscal tissue explants. Fibro-cartilagenous disks (3 mm diameter

相關內容

Select different protease inhibitor types based on your needs to prevent protein degradation during isolation and characterization and safeguard proteins in sample prep.

根據您的需求選擇不同類型的蛋白酶抑制劑,防止蛋白質在分離和表徵過程中降解,保障樣品預備過程中蛋白質的安全。

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