Phenytoin is an antiepileptic drug used in the prevention and treatment of seizures. This analytical reference standard is suitable as starting material for the preparation of calibrators and controls in phenytoin testing by GC/MS or LC-MS/MS. Phenytoin is sold under the trade name Dilantin®.
法律資訊
CERILLIANT is a registered trademark of Merck KGaA, Darmstadt, Germany
Dilantin is a registered trademark of Warner-Lambert Co.
Snap-N-Shoot is a registered trademark of Cerilliant Corporation
Snap-N-Spike is a registered trademark of Merck KGaA, Darmstadt, Germany
Journal of clinical laboratory analysis, 27(1), 1-4 (2013-01-18)
For many years, fluorescence polarization immunoassay (FPIA) on the TDx analyzer has been used for determination of free phenytoin concentration. Recently Abbott Laboratories decided to discontinue the TDx analyzer and related assays on this analyzer. Free phenytoin assay is also
Journal of analytical toxicology, 37(2), 102-109 (2013-01-18)
This study describes the development and validation of a gas chromatography-mass spectrometry (GC-MS) method to identify and quantitate phenytoin in brain microdialysate, saliva and blood from human samples. A solid-phase extraction (SPE) was performed with a nonpolar C8-SCX column. The
The persistent Na⁺ current (I(NaP)) is important for neuronal functions and can play a role in several pathologies, although it is small compared to the transient Na⁺ current (I(NaT)). Notably, I(NaP) is not a real persistent current because it undergoes
Tennessee medicine : journal of the Tennessee Medical Association, 106(4), 35-36 (2013-04-27)
Anticonvulsant Hypersensitivity Syndrome (AHS) is a rare complication of common drugs used today. It is unusual in that it occurs later than most other drug reactions, about two to six weeks after initiation of the offending agent. It also has
The Lancet. Neurology, 12(3), 244-252 (2013-01-29)
Many women of childbearing potential take antiepileptic drugs, but the cognitive effects of fetal exposure are uncertain. We aimed to assess effects of commonly used antiepileptic drugs on cognitive outcomes in children up to 6 years of age. In this
