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重要文件

D7631

Sigma-Aldrich

5,5-二甲基噁唑烷-2,4-二酮

同義詞:

DMO, NSC 30152, 二甲双酮

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About This Item

經驗公式(希爾表示法):
C5H7NO3
CAS號碼:
分子量::
129.11
EC號碼:
MDL號碼:
分類程式碼代碼:
12352100
PubChem物質ID:
NACRES:
NA.22
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形狀

powder

mp

77-80 °C (lit.)

儲存溫度

2-8°C

SMILES 字串

CC1(C)OC(=O)NC1=O

InChI

1S/C5H7NO3/c1-5(2)3(7)6-4(8)9-5/h1-2H3,(H,6,7,8)

InChI 密鑰

JYJFNDQBESEHJQ-UHFFFAOYSA-N

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應用

作为反应物,参与以下反应:
  • 苯并环镍或萘环镍β氧杂氮杂氯配合物的合成[1]
  • 用作组织蛋白酶K抑制剂[2]

参与药理学研究的分子包括:
  • 抗癫痫药生物等效仿制药的鉴定[3]
  • 筛选将能量代谢从线粒体呼吸转变为糖酵解的药物[4]
  • 溶解总胆管囊肿/胰胆管连接不良患者的蛋白塞[5]

象形圖

Health hazardExclamation mark

訊號詞

Warning

危險分類

Acute Tox. 4 Dermal - Acute Tox. 4 Inhalation - Acute Tox. 4 Oral - Carc. 2

儲存類別代碼

11 - Combustible Solids

水污染物質分類(WGK)

WGK 3

閃點(°F)

Not applicable

閃點(°C)

Not applicable

個人防護裝備

dust mask type N95 (US), Eyeshields, Gloves


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分析證明 (COA)

Lot/Batch Number

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D P Nolan et al.
European journal of biochemistry, 267(15), 4601-4614 (2000-07-21)
Conditions for the use of both [14C]methylamine and 5, 5-dimethyl[14C]oxa-azolidine-2,4-dione (DMO) to measure the H+ concentration of intracellular compartments of monomorphic long thin bloodstream forms of Trypanosoma brucei were established. Neither probe was actively transported or bound to internal components
Cunxi Wang et al.
Regulatory toxicology and pharmacology : RTP, 81, 171-182 (2016-10-30)
Dicamba tolerant (DT) soybean, cotton and maize were developed through constitutive expression of dicamba mono-oxygenase (DMO) in chloroplasts. DMO expressed in three DT crops exhibit 91.6-97.1% amino acid sequence identity to wild type DMO. All DMO forms maintain the characteristics
Jingxuan Wang et al.
Food & function, 10(8), 4823-4833 (2019-07-19)
Donkey milk is considered to be a valuable nutritional source. Deeper knowledge of the constituents of donkey milk is necessary. As multifunctional components of milk, oligosaccharides have been reported to have the potential to support intestine development. We studied the
Christian Danielsson et al.
Birth defects research. Part A, Clinical and molecular teratology, 79(8), 595-603 (2007-06-23)
The antiepileptic drugs (AEDs) phenytoin, phenobarbital, dimethadione, and carbamazepine cause a similar pattern of malformations in humans, with an increased risk after polytherapy. The teratogenicity has been linked to cardiac rhythm disturbances and hypoxic damage as a consequence of their
Hemal Mehta et al.
The British journal of ophthalmology, 102(4), 479-482 (2017-08-06)
To determine whether early vision gains predict long-term visual outcomes in the BEVORDEX randomised clinical trial of bevacizumab or dexamethasone implants for diabetic macular oedema. Post hoc analysis of 68 study eyes (77%) that completed 2 years follow-up of the

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