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Merck
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900914

Sigma-Aldrich

Methyltetrazine-NHS ester

≥95%

同義詞:

2,5-Dioxo-1-pyrrolidinyl 4-(6-methyl-1,2,4,5-tetrazin-3-yl)benzeneacetate

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About This Item

經驗公式(希爾表示法):
C15H13N5O4
CAS號碼:
分子量::
327.29
MDL號碼:
分類程式碼代碼:
12352108
NACRES:
NA.22

品質等級

化驗

≥95%

形狀

powder or crystals

反應適用性

reaction type: click chemistry
reagent type: cross-linking reagent

官能基

NHS ester

儲存溫度

−20°C

SMILES 字串

O=C(ON1C(CCC1=O)=O)CC(C=C2)=CC=C2C3=NN=C(C)N=N3

應用

Methyltetrazine-NHS ester has an N-hydroxysuccinimide (NHS) ester that can be reacted with primary amines and a methyltetrazine, which is reactive to trans-cyclooctenes. The NHS ester reacts with primary amines (e.g. side chain of lysine residues or aminosilane-coated surfaces) at neutral or slightly basic pH to form covalent bonds. The short spacer arm adds minimal mass to modified molecules (230.2 daltons). It is generally used in click chemistry applications in bioconjugate chemistry.

儲存類別代碼

11 - Combustible Solids

水污染物質分類(WGK)

WGK 3

閃點(°F)

Not applicable

閃點(°C)

Not applicable


分析證明 (COA)

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文章

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