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重要文件

81323

Sigma-Aldrich

聚乙二醇甲基醚

Poly(ethylene glycol) methyl ether
1 of 3 reviewers received a sample product or took part in a promotion

average MN 5,000, methoxy, hydroxyl

同義詞:

mPEG, 甲氧基聚乙二醇, 聚乙二醇单甲醚

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About This Item

線性公式:
CH3(OCH2CH2)nOH
CAS號碼:
MDL號碼:
分類程式碼代碼:
12162002
PubChem物質ID:
NACRES:
NA.23
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產品名稱

聚乙二醇甲基醚, average Mn 5,000

蒸汽密度

>1 (vs air)

蒸汽壓力

0.05 mmHg ( 20 °C)

形狀

flakes
powder or crystals

分子量

average Mn 5,000

mp

60-64 °C

Ω-end

hydroxyl

α-end

methoxy

SMILES 字串

O(CCO)C

InChI

1S/C3H8O2/c1-5-3-2-4/h4H,2-3H2,1H3

InChI 密鑰

XNWFRZJHXBZDAG-UHFFFAOYSA-N

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應用

聚(乙二醇)甲基醚(mPEG)是一种亲水性聚合物,可用于控制复合材料的柔韧性。mPEG可用于多种应用,例如药物递送、组织工程和其他生物学用途。[1][2][3]

其他說明

用于聚合物负载液相合成低聚糖的聚合物。[4]

儲存類別代碼

10 - Combustible liquids

水污染物質分類(WGK)

WGK 1

閃點(°F)

359.6 °F - closed cup

閃點(°C)

182 °C - closed cup

個人防護裝備

Eyeshields, Gloves


從最近期的版本中選擇一個:

分析證明 (COA)

Lot/Batch Number

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存取文件庫

S.P. Douglas et al.
Journal of the American Chemical Society, 113, 5095-5095 (1991)
Magnetite nanoparticles stabilized with polymeric bilayer of poly (ethylene glycol) methyl ether-poly (?-caprolactone) copolymers
Meerod S, et al.
Polymer, 49(18), 3950-3956 (2008)
Hamed Nosrati et al.
Pharmaceutical development and technology, 24(1), 89-98 (2018-01-09)
In this study, we designed a polymersome system for the controlled release of methotrexate (MTX) as an anticancer drug with the objective of improving the loading efficiency of the drug in polymersomes as well as achievement of an efficient control
Yvonne K Girard et al.
PloS one, 8(10), e75345-e75345 (2013-10-23)
The development of a suitable three dimensional (3D) culture system for anticancer drug development remains an unmet need. Despite progress, a simple, rapid, scalable and inexpensive 3D-tumor model that recapitulates in vivo tumorigenesis is lacking. Herein, we report on the
Kangan Li et al.
International journal of nanomedicine, 8, 2589-2600 (2013-07-28)
Development of dual-mode or multi-mode imaging contrast agents is important for accurate and self-confirmatory diagnosis of cancer. We report a new multifunctional, dendrimer-based gold nanoparticle (AuNP) as a dual-modality contrast agent for magnetic resonance (MR)/computed tomography (CT) imaging of breast

文章

Biofouling control essential for device performance and safety; minimize accumulation of biomolecules and bioorganisms.

Progress in biotechnology fields such as tissue engineering and drug delivery is accompanied by an increasing demand for diverse functional biomaterials. One class of biomaterials that has been the subject of intense research interest is hydrogels, because they closely mimic the natural environment of cells, both chemically and physically and therefore can be used as support to grow cells. This article specifically discusses poly(ethylene glycol) (PEG) hydrogels, which are good for biological applications because they do not generally elicit an immune response. PEGs offer a readily available, easy to modify polymer for widespread use in hydrogel fabrication, including 2D and 3D scaffold for tissue culture. The degradable linkages also enable a variety of applications for release of therapeutic agents.

Designing biomaterial scaffolds mimicking complex living tissue structures is crucial for tissue engineering and regenerative medicine advancements.

Questions

1–2 of 2 Questions  
  1. How can I determine the shelf life / expiration / retest date of this product?

    1 answer
    1. If this product has an expiration or retest date, it will be shown on the Certificate of Analysis (COA, CofA). If there is no retest or expiration date listed on the product's COA, we do not have suitable stability data to determine a shelf life. For these products, the only date on the COA will be the release date; a retest, expiration, or use-by-date will not be displayed.
      For all products, we recommend handling per defined conditions as printed in our product literature and website product descriptions. We recommend that products should be routinely inspected by customers to ensure they perform as expected.
      For products without retest or expiration dates, our standard warranty of 1 year from the date of shipment is applicable.
      For more information, please refer to the Product Dating Information document: https://www.sigmaaldrich.com/deepweb/assets/sigmaaldrich/marketing/global/documents/449/386/product-dating-information-mk.pdf

      Helpful?

  2. How is shipping temperature determined? And how is it related to the product storage temperature?

    1 answer
    1. Products may be shipped at a different temperature than the recommended long-term storage temperature. If the product quality is sensitive to short-term exposure to conditions other than the recommended long-term storage, it will be shipped on wet or dry-ice. If the product quality is NOT affected by short-term exposure to conditions other than the recommended long-term storage, it will be shipped at ambient temperature. As shipping routes are configured for minimum transit times, shipping at ambient temperature helps control shipping costs for our customers. For more information, please refer to the Storage and Transport Conditions document: https://www.sigmaaldrich.com/deepweb/assets/sigmaaldrich/marketing/global/documents/316/622/storage-transport-conditions-mk.pdf

      Helpful?

Reviews

1 of 3 reviewers received a sample product or took part in a promotion
1–2 of 3 Reviews  

Active Filters

    • Review 1
    • Votes 5
    1 out of 5 stars.

    High dispersity!

    Dispersity is 1.18! Not suitable for my experiment:(

    Helpful?

    1. Response from MilliporeSigma:

      We are sorry to hear this polydispersity value is not suitable for your application. Each lot is tested for polydispersity, the value is reported on the COA but we do not provide a specification range. The values from three of our past lots are 1.35, 1.35, and 1.34. You can search for the result of your lot by using the COA search on this page.

      If you observed a different polydispersity than what is listed on your lot specific COA, you can contact us for additional technical support. Please visit https://www.sigmaaldrich.com/US/en/support/customer-support to submit a Product Technical Inquiry.

  1. TR
    • Review 1
    • Votes 0
    1 out of 5 stars.

    Proton NMR spectrum of poly(etylene glycol)methyl ether does not indicate the structure!

    Dear SA,
    Your product MPEG5000 seems to have different structures/contaminants... In the spectra, by comparing -OCH3 end group protons with etylene protons, the degree of polymerisation calculated to be 50,7 instead of 113. Thus Mn is around 2260 g/mol (nor 5000 g/mol). Additionaly, there is an extra peak at 1,8-1,9 ppm is not related with MPEG5000 structure.. Our GPC study also indicates Mn around 2400 (not 5000) which fits well with NMR data... Please, reevaluate the structure of your product by considering our results...

    Helpful?

    1. Response from MilliporeSigma:

      We would like to investigate this further.

      Please visit https://www.sigmaaldrich.com/US/en/support/customer-support to submit a Product Technical Inquiry.

  2. 1 Ratings-Only Review

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