聚乙二醇 (PEG 和 PEO)
聚乙二醇 (PEG),又稱為聚氧化乙烯 (PEO) 或聚氧乙烯 (POE),是一種人工合成的、親水且具有生物相容性的聚醚。通常,分子量小於 20,000 g/mol 的材料稱為 PEG,而分子量大於 20,000 g/mol 的材料稱為 PEO。這些聚合物可溶解於水以及許多有機溶劑,例如乙醇、乙腈、甲苯、丙酮、二氯甲烷、己烷和氯仿。
PEG 的應用
PEG 無毒,常用於生物接合和表面功能化應用、生物醫學研究、藥物輸送、組織工程,以及食品和化妝品產業。PEG 聚合物鏈與分子的結合或非共價附著稱為 PEG 化。PEG 化方法可以增強水的生物相容性以及治療藥物的溶解性、穩定性和藥代動力學特性,從而提高其在靶向診斷和藥物傳輸中的安全性和效率。PEG 水凝膠常用於治療藥物的控釋、細胞培養支架、再生醫學、傷口癒合及組織工程。
PEG 衍生物和 PEG 連結劑
我們提供廣泛的定義良好的 PEG 產品組合,具有各種分子量、端功能、反應性和聚合物架構。
- 異組官能 PEG
- 同組官能 PEG
- 單官能 PEG
如需更深入的資訊,包括四種一般特性、主要工業應用和相關產品,請瀏覽我們的&?nbsp;聚乙二醇 (PEG) 和聚氧化乙烯 (PEO) 手冊.
。相關產品資源
- Article: Polyethylene Glycol Building Blocks for PEGylation
循環半衰期是新藥成功的關鍵因素。在這方面,聚乙二醇化或聚乙二醇化 (PEG-ing) - 用聚乙二醇鏈對從非多肽小分子到多肽和蛋白質、抗體片段、適應子和糖或寡核苷酸等各種潛在候選物進行修飾 - 具有許多優勢。
- Article: PEG Selection Guide
聚乙二醇 (PEG),有時也稱為聚氧化乙烯 (PEO),是一種環氧乙烷與水的縮合聚合物,具有多種化學特性,使其在生物、化學和醫藥應用方面非常有用。
- Tech Spotlight: Degradable Poly(ethylene glycol) Hydrogels for 2D and 3D Cell Culture
Progress in biotechnology fields such as tissue engineering and drug delivery is accompanied by an increasing demand for diverse functional biomaterials. One class of biomaterials that has been the subject of intense research interest is hydrogels, because they closely mimic the natural environment of cells, both chemically and physically and therefore can be used as support to grow cells. This article specifically discusses poly(ethylene glycol) (PEG) hydrogels, which are good for biological applications because they do not generally elicit an immune response. PEGs offer a readily available, easy to modify polymer for widespread use in hydrogel fabrication, including 2D and 3D scaffold for tissue culture. The degradable linkages also enable a variety of applications for release of therapeutic agents.
- Tech Spotlight: Polyethylene Glycol Building Blocks for PEGylation
Progress in biotechnology fields such as tissue engineering and drug delivery is accompanied by an increasing demand for diverse functional biomaterials. One class of biomaterials that has been the subject of intense research interest is hydrogels, because they closely mimic the natural environment of cells, both chemically and physically and therefore can be used as support to grow cells. This article specifically discusses poly(ethylene glycol) (PEG) hydrogels, which are good for biological applications because they do not generally elicit an immune response. PEGs offer a readily available, easy to modify polymer for widespread use in hydrogel fabrication, including 2D and 3D scaffold for tissue culture. The degradable linkages also enable a variety of applications for release of therapeutic agents.
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